Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | NCF1 | P14598 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR5A | P47898 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6678527 | 0.82 | POLB (0.46) | POLBHSD17B10MAPK1NPC1HTR3E | |
| SCHEMBL6678441 | 0.71 | CYP1A2 (0.42) | POLBHSD17B10MAPK1NPC1HTR3E | |
| SCHEMBL13425438 | 0.66 | POLB (0.49) | POLBHSD17B10MAPK1NPC1HTR3E | |
| SCHEMBL10037131 | 0.63 | HTR1A (0.57) | HSD17B10MAPK1HTR3EHTR3BCYP1A2 | |
| SCHEMBL18770820 | 0.62 | POLB (0.63) | POLBHSD17B10MAPK1NPC1HTR3E | |
| SCHEMBL8990319 | 0.62 | POLB (0.63) | POLBHSD17B10MAPK1NPC1HTR3E | |
| SCHEMBL30285929 | 0.62 | POLB (0.63) | POLBHSD17B10MAPK1NPC1HTR3E | |
| SCHEMBL19206396 | 0.61 | ALDH1A1 (0.42) | CYP1A2TSHRALDH1A1HPGDKMT2A | |
| SCHEMBL19343021 | 0.60 | POLB (0.61) | POLBHSD17B10MAPK1NPC1HTR3E | |
| SCHEMBL4216264 | 0.60 | HSD17B10 (0.48) | POLBHSD17B10MAPK1NPC1HTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1093475-B1 | CATALYST FOR THE POLYMERISATION OF OLEFINS | BOREALIS TECH OY (FI) | 2004-11-17 | — | — | EP | disclosed |
| US-6613851-B1 | Cyclic carbene- eta -ligand complexes for catalysis of olefin polymerization. | BOREALIS TECHNOLOGY OY (FI) | 2003-09-02 | — | — | US | disclosed |
| WO-2000078826-A1 | CATALYSTS | BOREALIS TECHNOLOGY OY (FI) | 2000-12-28 | — | — | WO | disclosed |