Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 3/20 | 0.41 |
| ▸ | FEN1 | P39748 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9352314 | 0.85 | NR4A2 (0.47) | KMT2AMEN1KDM4EMAPTRAB9A | |
| SCHEMBL891695 | 0.80 | ALDH1A1 (0.52) | KMT2AMEN1KDM4EMAPTHPGD | |
| SCHEMBL357341 | 0.80 | ALDH1A1 (0.52) | KMT2AMEN1KDM4EMAPTHPGD | |
| SCHEMBL728576 | 0.80 | ALDH1A1 (0.52) | KMT2AMEN1KDM4EMAPTHPGD | |
| SCHEMBL6678873 | 0.79 | ERCC5 (0.40) | ERCC5FEN1KMT2AMEN1KDM4E | |
| Acetaldehyde SCHEMBL11678453 | 0.77 | ALDH1A1 (0.48) | KMT2AMEN1KDM4EMAPTPTPN1 | |
| SCHEMBL23226919 | 0.76 | LMNA (0.41) | KMT2AMEN1KDM4EMAPTBACE1 | |
| SCHEMBL27715967 | 0.76 | BCHE (0.39) | KMT2AMEN1KDM4EMAPTBACE1 | |
| SCHEMBL9496987 | 0.75 | AKR1C3 (0.52) | KMT2AMAPTCES1MAPK1TDP1 | |
| SCHEMBL12678685 | 0.75 | BACE1 (0.56) | KMT2AKDM4EMAPTBACE1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0412933-B1 | Coating compositions | CIBA GEIGY AG (CH) | 1994-09-14 | — | — | EP | disclosed |
| US-5183842-A | Mixture of ketoacid and amine with film-forming binder, curing | CIBA-GEIGY CORPORATION (US) | 1993-02-02 | — | — | US | disclosed |
| US-5128396-A | Corrosion inhibiting primers on metallic substrates | CIBA-GEIGY CORPORATION (US) | 1992-07-07 | — | — | US | disclosed |
| EP-0412933-A1 | Coating compositions | CIBA-GEIGY AG (CH) | 1991-02-13 | — | — | EP | disclosed |