Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 3/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 4/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6677388 | 0.99 | KDM1A (0.43) | KDM1ARCOR1NOS1NOS2ROCK2 | |
| SCHEMBL6677091 | 0.82 | ENPP2 (0.44) | NOS1NOS2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL6678577 | 0.81 | NOS1 (0.41) | NOS1NOS2GRIN2DGRIN3BGRIN1 | |
| Hydrochloric Acid SCHEMBL6675347 | 0.81 | ENPP2 (0.43) | NOS1NOS2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL3728364 | 0.80 | NOS1 (0.50) | KDM1ARCOR1NOS1NOS2ROCK2 | |
| SCHEMBL6675110 | 0.79 | TAAR1 (0.47) | NOS1NOS2GRIN2DGRIN3BGRIN1 | |
| Hydrochloric Acid SCHEMBL6677787 | 0.79 | MAPT (0.41) | NOS1NOS2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL27477898 | 0.78 | KDM1A (0.43) | KDM1ARCOR1NOS1NOS2ROCK2 | |
| SCHEMBL6679466 | 0.78 | KDM1A (0.43) | KDM1ARCOR1NOS1NOS2ROCK2 | |
| SCHEMBL6678027 | 0.78 | BACE1 (0.40) | MAPTGAAMEN1NPC1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | claimed |