Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | PIM1 | P11309 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29819864 | 1.00 | ACHE (0.57) | ACHECA12PIM1L3MBTL1LMNA | |
| SCHEMBL13442859 | 0.93 | CASP3 (0.62) | ACHECA12PIM1L3MBTL1CASP3 | |
| SCHEMBL29195349 | 0.88 | PIM1 (0.51) | ACHECA12PIM1L3MBTL1LMNA | |
| SCHEMBL13952129 | 0.87 | CASP3 (0.47) | ACHECA12CASP3 | |
| SCHEMBL28737150 | 0.87 | KDM4E (0.63) | CA12L3MBTL1LMNAALDH1A1 | |
| SCHEMBL3131037 | 0.84 | RECQL (0.47) | ACHECASP3 | |
| SCHEMBL14302321 | 0.83 | PIM1 (0.47) | ACHECA12PIM1L3MBTL1LMNA | |
| SCHEMBL18669187 | 0.82 | ACHE (0.61) | ACHECASP3 | |
| SCHEMBL18668918 | 0.82 | CASP3 (0.54) | ACHECASP3 | |
| SCHEMBL18954909 | 0.81 | ALDH1A1 (0.71) | ACHECA12LMNATHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110746342-B | Preparation method of hydroxy lactam | 南方科技大学 | 2023-05-16 | — | — | CN | disclosed |
| CN-110734384-B | Preparation method of hydroxyamide | 南方科技大学 | 2022-09-20 | — | — | CN | disclosed |
| CN-110746342-A | Preparation method of hydroxy lactam | 南方科技大学 | 2020-02-04 | — | — | CN | disclosed |
| CN-110734384-A | Preparation method of hydroxyamides | 南方科技大学 | 2020-01-31 | — | — | CN | disclosed |
| WO-2017049409-A1 | COMPOSITIONS FOR PROMOTING READTHROUGH OF PREMATURE TERMINATION CODONS, AND METHODS OF USING THE SAME | THE CENTRE FOR DRUG RESEARCH AND DEVELOPMENT (CA) | 2017-03-30 | — | — | WO | disclosed |
| WO-2017049409-A1 | COMPOSITIONS FOR PROMOTING READTHROUGH OF PREMATURE TERMINATION CODONS, AND METHODS OF USING THE SAME | THE CENTRE FOR DRUG RESEARCH AND DEVELOPMENT (CA) | 2017-03-30 | — | — | WO | disclosed |
| EP-1419126-A1 | FLUOROUS NUCLEOPHILIC SUBSTITUTION OF ALCOHOLS AND REAGENTS FOR USE THEREIN | UNIVERSITY OF PITTSBURGH (US) | 2004-05-19 | — | — | EP | disclosed |
| WO-2003016246-A1 | FLUOROUS NUCLEOPHILIC SUBSTITUTION OF ALCOHOLS AND REAGENTS FOR USE THEREIN | UNIVERSITY OF PITTSBURGH (US) | 2003-02-27 | — | — | WO | disclosed |