SCHEMBL6679604

SCHEMBL6679604

CCCC(Br)c1ccc(Cl)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 5/20 0.41
SLC6A4 P31645 5/20 0.41
SLC6A3 Q01959 5/20 0.41
ADRB2 P07550 1/20 0.41
TSHR P16473 2/20 0.38
MAPK1 P28482 2/20 0.38
HIF1A Q16665 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
AOC3 Q16853 2/20 0.38
LMNA P02545 3/20 0.37
TP53 P04637 1/20 0.37
HPGD P15428 1/20 0.37
FFAR2 O15552 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MMP2 P08253 1/20 0.36
MMP9 P14780 1/20 0.36
BRD4 O60885 1/20 0.35
PPARG P37231 2/20 0.35
PPARA Q07869 2/20 0.35
CYP2A6 P11509 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7217195 0.88 SLC6A2 (0.44) SLC6A2SLC6A4SLC6A3ADRB2TSHR
SCHEMBL10609018 0.83 MMP2 (0.42) SLC6A2SLC6A4SLC6A3ADRB2TSHR
SCHEMBL7112239 0.82 ADRB2 (0.44) SLC6A2SLC6A4SLC6A3ADRB2TSHR
SCHEMBL9789948 0.80 CHRNA7 (0.38) SLC6A2SLC6A4SLC6A3TDP1LMNA
SCHEMBL6173982 0.80 PYCR1 (0.39) SLC6A2SLC6A4SLC6A3HPGDSMN1; SMN2
SCHEMBL2125627 0.78 ALDH1A1 (0.40) SLC6A2SLC6A4SLC6A3AOC3LMNA
SCHEMBL7113377 0.78 AOC3 (0.42) SLC6A2SLC6A4SLC6A3ADRB2TSHR
SCHEMBL687847 0.77 AOC3 (0.46) AOC3LMNA
SCHEMBL13265139 0.77 AOC3 (0.46) AOC3LMNA
SCHEMBL10291752 0.77 ESR1 (0.47) SLC6A2SLC6A4SLC6A3ADRB2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0985649-B1 Method for producing an aromatic compound having an alkyl group with at least three carbon atoms TORAY INDUSTRIES (JP) 2004-11-24 EP disclosed
US-6462248-B1 THROUGH CONVERSION, ISOMERIZATION AND/OR ADSORPTIVE SEPARATION OF AROMATIC COMPOUNDS TORAY INDUSTRIES, INC. (JP) 2002-10-08 US disclosed
EP-0985649-A2 Method for producing an aromatic compound having an alkyl group with at least three carbon atoms TORAY INDUSTRIES, INC. (JP) 2000-03-15 EP disclosed
EP-0772594-A1 IMINOXYCARBOXYLATES AND DERIVATIVES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS Abbott Laboratories (US) 1997-05-14 EP disclosed
WO-1996002507-A1 IMINOXYCARBOXYLATES AND DERIVATIVES AS INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS ABBOTT LABORATORIES (US) 1996-02-01 WO disclosed
US-4017631-A MICROBIOCIDES JANSSEN PHARMACEUTICA N.V. (BE) 1977-04-12 US disclosed
US-3991202-A ANTIMICROBIALS JANSSEN PHARMACEUTICA N.V. (BE) 1976-11-09 US disclosed