SCHEMBL667969

SCHEMBL667969

Cc1cn([C@@H]2O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)C(O)C2O)c(=O)nc1N

nearest known ligand 0.74

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
P2RY2 P41231 13/20 0.68
P2RY6 Q15077 5/20 0.61
P2RY4 P51582 3/20 0.61
ENPP1 P22413 2/20 0.59
P2RY1 P47900 2/20 0.59
P2RX1 P51575 1/20 0.59
P2RX3 P56373 1/20 0.59
P2RY11 Q96G91 1/20 0.59
P2RX4 Q99571 1/20 0.59
RNASEL Q05823 1/20 0.58
P2RY12 Q9H244 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16805401 1.00 P2RY2 (0.68) P2RY2P2RY6P2RY4ENPP1P2RY1
SCHEMBL624932 1.00 P2RY2 (0.68) P2RY2P2RY6P2RY4ENPP1P2RY1
SCHEMBL18609299 1.00 P2RY2 (0.68) P2RY2P2RY6P2RY4ENPP1P2RY1
SCHEMBL17210998 1.00 P2RY2 (0.68) P2RY2P2RY6P2RY4ENPP1P2RY1
SCHEMBL14661260 0.98 P2RY2 (0.65) P2RY2P2RY6P2RY4ENPP1P2RY1
SCHEMBL14661258 0.98 P2RY2 (0.65) P2RY2P2RY6P2RY4ENPP1P2RY1
SCHEMBL16805307 0.92 P2RY2 (0.57) P2RY2P2RY6P2RY4ENPP1P2RY1
SCHEMBL903054 0.90 FBP1 (0.57) P2RY2P2RY6P2RY4P2RY1P2RY11
SCHEMBL17809090 0.90 FBP1 (0.57) P2RY2P2RY6P2RY4P2RY1P2RY11
SCHEMBL3504116 0.90 FBP1 (0.57) P2RY2P2RY6P2RY4P2RY1P2RY11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1046 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250161488-A1 THERAPEUTIC mRNA THE UNIVERSITY OF MELBOURNE (AU) 2025-05-22 US claimed
WO-2025061107-A1 COMPOSITION COMPRISING MRNA ENCODING INFLUENZA VIRUS HA PROTEIN AND USE THEREOF ARGORNA PHARMACEUTICALS CO., LTD. (CN) 2025-03-27 WO claimed
CN-119679931-A MRNA composition containing coded influenza virus HA protein and application thereof 阿格纳生物制药有限公司 2025-03-25 CN claimed
CN-119375375-A Method for detecting nucleotide, cap analogue and nucleic acid in vitro transcription product 楷拓生物科技(苏州)有限公司 2025-01-28 CN claimed
CN-119345129-A Cyclic IL-10mRNA nano preparation and preparation method and application thereof 环信生物科技(泰州)有限公司 2025-01-24 CN claimed
CN-119264229-A Vaccine and composition based on S protein of different omnikom variants of SARS-CoV-2 阿格纳生物制药有限公司 2025-01-07 CN claimed
US-20240415958-A1 MESSENGER RNA THERAPY FOR TREATMENT OF ARTICULAR DISEASE TRANSLATE BIO INC (US) 2024-12-19 US claimed
US-20240350619-A1 VACCINES AND COMPOSITIONS BASED ON SARS-COV-2 S PROTEIN GUANGZHOU RIBOBIO CO., LTD. (CN) 2024-10-24 US claimed
US-11998601-B2 Messenger RNA therapy for treatment of articular disease TRANSLATE BIO, INC. (US) 2024-06-04 US claimed
CN-113925975-B Preparation method of p53 and UTX messenger RNA nanoparticles and application of messenger RNA 杭州师范大学 2024-05-28 CN claimed
US-20160145346-A1 RNA-CODED ANTIBODY CUREVAC AG (DE) 2016-05-26 US claimed
EP-2968586-A2 CFTR MRNA COMPOSITIONS AND RELATED METHODS AND USES Shire Human Genetic Therapies, Inc. (US) 2016-01-20 EP claimed
WO-2014153052-A9 CFTR MRNA COMPOSITIONS AND RELATED METHODS AND USES SHIRE HUMAN GENETIC THERAPIES, INC. (US) 2015-08-06 WO claimed
WO-2014153052-A2 CFTR MRNA COMPOSITIONS AND RELATED METHODS AND USES SHIRE HUMAN GENETIC THERAPIES, INC. (US) 2014-09-25 WO claimed
US-20130195867-A1 RNA-CODED ANTIBODY CUREVAC GMBH (DE) 2013-08-01 US claimed
US-20100189729-A1 RNA-CODED ANTIBODY CURVAC GMBH (DE) 2010-07-29 US claimed
EP-2101823-A2 RNA-CODED ANTIBODY Curevac GmbH (DE) 2009-09-23 EP claimed
WO-2008083949-A2 RNA-CODED ANTIBODY CUREVAC GMBH (DE) 2008-07-17 WO claimed
EP-1848827-A2 METHODS AND COMPOSITIONS FOR TAGGING AND IDENTIFYING POLYNUCLEOTIDES Compass Genetics, Llc (US) 2007-10-31 EP claimed
WO-2006086210-A2 METHODS AND COMPOSITIONS FOR TAGGING AND IDENTIFYING POLYNUCLEOTIDES COMPASS GENETICS, LLC (US) 2006-08-17 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160145346-A1 RNA-CODED ANTIBODY TRDMT1, NSUN3, POLRMT P2RY2 3997/4885P2RY6 3779/4885P2RY4 3748/4885
US-20240415958-A1 MESSENGER RNA THERAPY FOR TREATMENT OF ARTICULAR DISEASE NSUN3, RNMT, TRDMT1 P2RY2 3741/4885P2RY6 3298/4885P2RY4 4107/4885
US-11998601-B2 Messenger RNA therapy for treatment of articular disease NSUN3, RNMT, TRDMT1 P2RY2 3741/4885P2RY6 3298/4885P2RY4 4107/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.