Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 17/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 9/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6678979 | 0.89 | PDGFRB (0.43) | S1PR1S1PR3PTGS1 | |
| SCHEMBL6677053 | 0.89 | ITGB1 (0.44) | S1PR1S1PR3OPRL1 | |
| SCHEMBL6685612 | 0.87 | S1PR1 (0.46) | S1PR1S1PR3 | |
| SCHEMBL6677401 | 0.85 | SORT1 (0.39) | S1PR1S1PR3TRPV4 | |
| SCHEMBL7083682 | 0.84 | CA12 (0.45) | TRPV4PTGS1 | |
| SCHEMBL6499114 | 0.84 | HDAC7 (0.47) | OPRL1 | |
| SCHEMBL6489781 | 0.84 | L3MBTL1 (0.47) | OPRL1 | |
| SCHEMBL6683660 | 0.81 | S1PR1 (0.48) | S1PR1S1PR3PTGS1 | |
| SCHEMBL6638338 | 0.81 | S1PR1 (0.43) | S1PR1S1PR3 | |
| SCHEMBL7081444 | 0.81 | TP53 (0.43) | OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1472226-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003045921-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-06-05 | — | — | WO | disclosed |