Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORT1 | Q99523 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 12/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 7/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6679699 | 0.85 | S1PR1 (0.43) | S1PR1S1PR3TRPV4 | |
| SCHEMBL6498923 | 0.83 | APOB (0.43) | SORT1RXFP1 | |
| SCHEMBL6685612 | 0.82 | S1PR1 (0.46) | RXFP1S1PR1S1PR3 | |
| SCHEMBL6679626 | 0.80 | SORT1 (0.40) | SORT1S1PR1S1PR3PTGES | |
| SCHEMBL6677053 | 0.77 | ITGB1 (0.44) | S1PR1S1PR3 | |
| SCHEMBL6680191 | 0.77 | LMNA (0.38) | RXFP1S1PR1S1PR3 | |
| SCHEMBL6683684 | 0.76 | HTR2A (0.47) | S1PR1S1PR3 | |
| SCHEMBL6787835 | 0.76 | MTTP (0.47) | RXFP1 | |
| SCHEMBL6678979 | 0.75 | PDGFRB (0.43) | S1PR1S1PR3 | |
| SCHEMBL6492113 | 0.74 | MAPKAPK2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1472226-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003045921-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-06-05 | — | — | WO | disclosed |