Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.53 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.40 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9519111 | 0.85 | ESR1 (0.55) | ESR1ESR2FAAHPTGS1PTGS2 | |
| SCHEMBL9520092 | 0.85 | ESR1 (0.55) | ESR1ESR2FAAHPTGS1PTGS2 | |
| SCHEMBL545393 | 0.85 | ESR1 (0.55) | ESR1ESR2FAAHPTGS1PTGS2 | |
| SCHEMBL2641075 | 0.82 | ABCB11 (0.52) | ESR1ESR2TRPA1ABCB11CYP2C9 | |
| SCHEMBL3193540 | 0.78 | ESR1 (0.47) | ESR1ESR2FAAHPTGS1PTGS2 | |
| SCHEMBL6641065 | 0.77 | ESR1 (0.45) | ESR1ESR2TRPA1ABCB11FAAH | |
| SCHEMBL13631389 | 0.76 | ABCB11 (0.44) | ESR1ESR2TRPA1ABCB11CYP2C9 | |
| SCHEMBL10130853 | 0.75 | LPL (0.45) | ESR1ESR2TRPA1ABCB11 | |
| SCHEMBL9694221 | 0.75 | ABCB11 (0.47) | ESR1ESR2TRPA1ABCB11PTGS2 | |
| SCHEMBL6933308 | 0.75 | ABCB11 (0.47) | ESR1ESR2TRPA1ABCB11CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901043-B1 | Radiation-sensitive resin composition | JSR CORP (JP) | 2004-10-27 | — | — | EP | disclosed |