Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.55 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.55 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.55 |
| ▸ | ALB | P02768 | 1/20 | 0.55 |
| ▸ | RARB | P10826 | 1/20 | 0.55 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 1/20 | 0.55 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.55 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.55 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9520092 | 1.00 | ESR1 (0.55) | ESR1ESR2PTGS1PTGS2ALOX5 | |
| SCHEMBL9519111 | 1.00 | ESR1 (0.55) | ESR1ESR2PTGS1PTGS2ALOX5 | |
| Sulfamate SCHEMBL9451526 | 0.88 | EPHX1 (0.51) | ESR1ESR2PTGS1PTGS2ALOX5 | |
| SCHEMBL6680010 | 0.85 | ESR1 (0.53) | ESR1ESR2PTGS1PTGS2ALOX5 | |
| SCHEMBL2641075 | 0.83 | ABCB11 (0.52) | ESR1ESR2CYP2C9TSHR | |
| SCHEMBL27876016 | 0.81 | PTGS1 (0.53) | ESR1PTGS1PTGS2ALOX5LMNA | |
| SCHEMBL11241173 | 0.79 | ESR1 (0.52) | ESR1ESR2PTGS1PTGS2ALOX5 | |
| SCHEMBL9055850 | 0.78 | FAAH (0.55) | ESR1ESR2PTGS1PTGS2ALOX5 | |
| SCHEMBL12327017 | 0.78 | TAAR1 (0.56) | ESR1ESR2PTGS1PTGS2ALOX5 | |
| SCHEMBL28289491 | 0.78 | PTGS1 (0.50) | ESR1ESR2PTGS1PTGS2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119390724-A | Synthesis method of phosphorous acid diester compound | 兰州大学 | 2025-02-07 | — | — | CN | claimed |
| CN-108238907-A | 2- (4- isobutyl phenenyls) propionic acid pharmaceutical synthesis method | 成都奥卡特科技有限公司 | 2018-07-03 | — | — | CN | claimed |
| EP-0374850-B1 | Method for preparing alpha-(4-isobutylphenyl)propionic acid or its precursor | NIPPON PETROCHEMICALS CO LTD (JP) | 1994-03-09 | — | — | EP | claimed |
| US-5260477-A | Multistage process of catalytic dehydrogenation and reaction with carbon monoxide then hydrogenation | NIPPON PETROCHEMICALS CO., LTD. (JP) | 1993-11-09 | — | — | US | claimed |
| US-5001283-A | Process for preparing aromatic alkanols | MOBIL OIL CORP. (US) | 1991-03-19 | — | — | US | claimed |
| EP-0374850-A1 | Method for preparing alpha-(4-isobutylphenyl)propionic acid or its precursor | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1990-06-27 | — | — | EP | claimed |
| EP-0088147-A1 | A new compound with analgesic, antiinflammatory and antipyretic activity, process for the preparation thereof and pharmaceutical compositions therefrom | AUSONIA FARMACEUTICI S.r.l. (IT) | 1983-09-14 | — | — | EP | claimed |
| CN-122036488-A | Method for oxidizing primary alcohol to carboxylic acid by oxygen without metal catalysis | 浙江工业大学 | 2026-05-15 | — | — | CN | disclosed |
| US-12421200-B2 | Manganese-catalysed hydrogenation of esters | UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2025-09-23 | — | — | US | disclosed |
| CN-119390724-A | Synthesis method of phosphorous acid diester compound | 兰州大学 | 2025-02-07 | — | — | CN | disclosed |
| US-20250027118-A1 | PHENYL ALCOHOLS FROM GAS FERMENTATION | LANZATECH, INC. | 2025-01-23 | — | — | US | disclosed |
| WO-2025019550-A1 | PHENYL ALCOHOLS FROM GAS FERMENTATION | LANZATECH, INC. (US) | 2025-01-23 | — | — | WO | disclosed |
| CN-119040917-A | Electrochemical S-2-pyridylalkyl sulfide synthesis method | 杭州师范大学 | 2024-11-29 | — | — | CN | disclosed |
| EP-0403185-A2 | Compounds having one or more aminosulfonyloxy radicals useful as pharmaceuticals | A.H. ROBINS COMPANY, INCORPORATED (US) | 1990-12-19 | — | — | EP | disclosed |
| US-4954325-A | Adsorbent; alkylation, hydrocracking catalyst | MOBIL OIL CORP. (US) | 1990-09-04 | — | — | US | disclosed |
| EP-0226566-B1 | OXIDATION OF 2-ARYLPROPANALS | MONSANTO COMPANY (US) | 1990-08-29 | — | — | EP | disclosed |
| EP-0374850-A1 | Method for preparing alpha-(4-isobutylphenyl)propionic acid or its precursor | NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) | 1990-06-27 | — | — | EP | disclosed |
| EP-0328125-A2 | Process for the enzymatic separation of the optical isomers of racemic alpha-alkyl-substituted primary alcohols | ISTITUTO GUIDO DONEGANI S.p.A. (IT) | 1989-08-16 | — | — | EP | disclosed |
| US-4435591-A | 2-(4-ISOBUTYLPHENYL)-1-PROPANOL-3,4,5-TRIMETHOXY-BENZOATE | AUSONIA FARMACEUTICI S.R.L. (IT) | 1984-03-06 | — | — | US | disclosed |
| EP-0088147-A1 | A new compound with analgesic, antiinflammatory and antipyretic activity, process for the preparation thereof and pharmaceutical compositions therefrom | AUSONIA FARMACEUTICI S.r.l. (IT) | 1983-09-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12421200-B2 | Manganese-catalysed hydrogenation of esters | ADH5, HDHD5, ADH1A | ESR1 1070/4885ESR2 923/4885PTGS1 4063/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.