SCHEMBL6680116

SCHEMBL6680116

CC1=NN(c2ccc(S(=O)(=O)O)cc2)C(=O)C1=CC=Cc1c(C)nn(-c2ccc(S(=O)(=O)O)cc2)c1O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
CA9 Q16790 1/20 0.53
KAT8 Q9H7Z6 2/20 0.50
MAPT P10636 10/20 0.48
KMT2A Q03164 10/20 0.48
ALDH1A1 P00352 9/20 0.48
MEN1 O00255 8/20 0.48
MAPK1 P28482 7/20 0.48
L3MBTL1 Q9Y468 7/20 0.48
SMN1; SMN2 Q16637 4/20 0.48
POLB P06746 7/20 0.47
HTT P42858 5/20 0.47
TDP1 Q9NUW8 4/20 0.47
LMNA P02545 2/20 0.47
HPGD P15428 1/20 0.46
HSD17B10 Q99714 1/20 0.46
PKM P14618 2/20 0.42
OPRK1 P41145 2/20 0.42
NPSR1 Q6W5P4 3/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10036042 1.00 CA1 (0.53) CA1CA2CA9KAT8MAPT
SCHEMBL6679978 1.00 CA1 (0.53) CA1CA2CA9KAT8MAPT
SCHEMBL14197585 1.00 CA1 (0.53) CA1CA2CA9KAT8MAPT
SCHEMBL4825033 0.96 KAT8 (0.48) CA1CA2CA9KAT8MAPT
SCHEMBL3188484 0.96 KAT8 (0.48) CA1CA2CA9KAT8MAPT
SCHEMBL6680125 0.96 KAT8 (0.48) CA1CA2CA9KAT8MAPT
SCHEMBL13763582 0.96 KAT8 (0.48) CA1CA2CA9KAT8MAPT
SCHEMBL6678634 0.95 KAT8 (0.48) CA1CA2CA9KAT8MAPT
SCHEMBL6678627 0.95 KAT8 (0.48) CA1CA2CA9KAT8MAPT
SCHEMBL6679975 0.91 CA1 (0.52) CA1CA2CA9KAT8MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1033965-B1 AGENTS AND METHOD FOR PRODUCING SEMI-PERMANENT COLORATIONS OF KERATIN FIBERS WELLA AG (DE) 2004-11-24 EP claimed
EP-0980236-B1 COLOURANT AND METHOD FOR PRODUCING TEMPORARY HAIR COLOURS WELLA AG (DE) 2003-04-23 EP claimed
US-6312478-B1 TWO COMPONENT KIT; ONE COMPONENT IS A COLORANT COMPRISING A MONOMETHINE OR POLYMETHINE DYE; SECOND COMPONENT CONSISTING OF A DECOLORIZING AGENT WELLA AKTIENGESELLSCHAFT (DE) 2001-11-06 US claimed
EP-1033965-A2 AGENTS AND METHOD FOR PRODUCING SEMI-PERMANENT COLORATIONS OF KERATIN FIBERS Wella Aktiengesellschaft (DE) 2000-09-13 EP claimed
WO-1999059529-A2 AGENTS AND METHOD FOR PRODUCING SEMI-PERMANENT COLORATIONS OF KERATIN FIBERS WELLA AKTIENGESELLSCHAFT (DE) 1999-11-25 WO claimed
US-12569470-B2 Vasodilator and use thereof BIORADICAL RESEARCH INSTITUTE CORP. (JP) 2026-03-10 US disclosed
US-20230330066-A1 Vasodilator and Use Thereof BIORADICAL RESEARCH INSTITUTE CORP. (JP) 2023-10-19 US disclosed
US-20220110916-A1 Antioxidant and Use Thereof BIORADICAL RESEARCH INSTITUTE CORP. (JP) 2022-04-14 US disclosed
US-20070176153-A1 ELECTROMAGNETIC WAVE SHIELDING FILM, METHOD OF MANUFACTURING THE SAME, ELECTROMAGNETIC WAVE SHIELDING FILM FOR PLASMA DISPLAY PANEL, AND OPTICAL FILM KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-08-02 US disclosed
EP-1033965-B1 AGENTS AND METHOD FOR PRODUCING SEMI-PERMANENT COLORATIONS OF KERATIN FIBERS WELLA AG (DE) 2004-11-24 EP disclosed
EP-0980236-B1 COLOURANT AND METHOD FOR PRODUCING TEMPORARY HAIR COLOURS WELLA AG (DE) 2003-04-23 EP disclosed
US-6361571-B1 USING TAUTOMERIC NONOXIDATIVE DYES AND POLYMETHINE DYES WELLA AKTIENGESELLSCHAFT (DE) 2002-03-26 US disclosed
US-6312478-B1 TWO COMPONENT KIT; ONE COMPONENT IS A COLORANT COMPRISING A MONOMETHINE OR POLYMETHINE DYE; SECOND COMPONENT CONSISTING OF A DECOLORIZING AGENT WELLA AKTIENGESELLSCHAFT (DE) 2001-11-06 US disclosed
EP-1033965-A2 AGENTS AND METHOD FOR PRODUCING SEMI-PERMANENT COLORATIONS OF KERATIN FIBERS Wella Aktiengesellschaft (DE) 2000-09-13 EP disclosed
EP-0980236-A1 COLOURANT AND METHOD FOR PRODUCING TEMPORARY HAIR COLOURS Wella Aktiengesellschaft (DE) 2000-02-23 EP disclosed
WO-1999059529-A2 AGENTS AND METHOD FOR PRODUCING SEMI-PERMANENT COLORATIONS OF KERATIN FIBERS WELLA AKTIENGESELLSCHAFT (DE) 1999-11-25 WO disclosed
WO-1999044569-A1 COLOURANT AND METHOD FOR PRODUCING TEMPORARY HAIR COLOURS WELLA AKTIENGESELLSCHAFT (DE) 1999-09-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230330066-A1 Vasodilator and Use Thereof NOX4, NOX1, NOX5 CA1 4337/4885CA2 920/4885CA9 4291/4885
US-12569470-B2 Vasodilator and use thereof ROS1, NOX3, ADRB3 CA1 3222/4885CA2 476/4885CA9 3327/4885
US-20220110916-A1 Antioxidant and Use Thereof GPX1, GPX4, SOD1 CA1 3691/4885CA2 2796/4885CA9 4381/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.