Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SELL | P14151 | 1/20 | 0.31 |
| ▸ | SELP | P16109 | 1/20 | 0.31 |
| ▸ | SELE | P16581 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34511 | 0.87 | SELL (0.36) | ALDH1A1NPSR1POLBMAPTHTT | |
| SCHEMBL6677918 | 0.75 | — | — | |
| SCHEMBL6681602 | 0.75 | KDM4E (0.35) | ALDH1A1KDM4E | |
| SCHEMBL6679629 | 0.73 | NR1I2 (0.32) | POLBSMN1; SMN2 | |
| SCHEMBL6678739 | 0.73 | DPP4 (0.35) | ALDH1A1MAPTKDM4E | |
| SCHEMBL8028616 | 0.70 | GABRA1 (0.37) | ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL6681680 | 0.69 | ALDH1A1 (0.35) | ALDH1A1NPSR1POLBMAPTHTT | |
| SCHEMBL16341301 | 0.69 | ALDH1A1 (0.35) | ALDH1A1NPSR1POLBMAPTHTT | |
| SCHEMBL6678521 | 0.68 | C5AR1 (0.40) | ALDH1A1POLBMAPTSMN1; SMN2 | |
| SCHEMBL283987 | 0.67 | ALDH1A1 (0.38) | HRH3ALDH1A1NPSR1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1093475-B1 | CATALYST FOR THE POLYMERISATION OF OLEFINS | BOREALIS TECH OY (FI) | 2004-11-17 | — | — | EP | disclosed |
| US-6613851-B1 | Cyclic carbene- eta -ligand complexes for catalysis of olefin polymerization. | BOREALIS TECHNOLOGY OY (FI) | 2003-09-02 | — | — | US | disclosed |
| EP-1093475-A1 | CATALYST FOR THE POLYMERISATION OF OLEFINS | Borealis Technology Oy (FI) | 2001-04-25 | — | — | EP | disclosed |
| WO-2000001739-A1 | CATALYST FOR THE POLYMERISATION OF OLEFINS | BOREALIS TECHNOLOGY OY (FI) | 2000-01-13 | — | — | WO | disclosed |