SCHEMBL6681602

SCHEMBL6681602

Cc1cc(C)c(N2[C]N([Si](C)(C)C)C=C2)c(C)c1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34511 0.82 SELL (0.36) KDM4EALDH1A1
SCHEMBL6680158 0.75 HRH3 (0.32) KDM4EALDH1A1
SCHEMBL6677918 0.70
SCHEMBL6678739 0.69 DPP4 (0.35) KDM4EALDH1A1
SCHEMBL18527604 0.66 CYP2D6 (0.35) KDM4EALDH1A1
SCHEMBL6679629 0.66 NR1I2 (0.32)
SCHEMBL8028616 0.66 GABRA1 (0.37) ALDH1A1
SCHEMBL16341301 0.65 ALDH1A1 (0.35) KDM4EALDH1A1
SCHEMBL6681680 0.65 ALDH1A1 (0.35) KDM4EALDH1A1
SCHEMBL6678521 0.64 C5AR1 (0.40) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1093475-B1 CATALYST FOR THE POLYMERISATION OF OLEFINS BOREALIS TECH OY (FI) 2004-11-17 EP disclosed
US-6613851-B1 Cyclic carbene- eta -ligand complexes for catalysis of olefin polymerization. BOREALIS TECHNOLOGY OY (FI) 2003-09-02 US disclosed