Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGAV | P06756 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | RXRG | P48443 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6692161 | 0.79 | CES2 (0.35) | CES2IDO1ADRB1 | |
| SCHEMBL2432674 | 0.78 | TSHR (0.47) | CES2IDO1MAPTALDH1A1TSHR | |
| SCHEMBL10379650 | 0.78 | CES2 (0.39) | CES2IDO1MAPTRXRARXRB | |
| SCHEMBL5077943 | 0.76 | LPL (0.43) | CES2 | |
| SCHEMBL7784283 | 0.76 | CES2 (0.33) | CES2IDO1ITGB3ITGAV | |
| SCHEMBL7859828 | 0.75 | CES2 (0.44) | CES2IDO1ALDH1A1TSHRCES1 | |
| SCHEMBL14227219 | 0.74 | CES2 (0.32) | CES2 | |
| SCHEMBL14227199 | 0.74 | TSHR (0.38) | CES2IDO1MAPTRXRARXRB | |
| SCHEMBL440959 | 0.74 | CES2 (0.58) | CES2IDO1ADRB1MAPTRAPGEF4 | |
| SCHEMBL8587206 | 0.71 | CES2 (0.33) | CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1137641-B1 | PROCESS FOR PREPARING PYRIDAZIN-3-ON DERIVATIVES | SUMITOMO CHEMICAL CO (JP) | 2004-11-10 | — | — | EP | disclosed |
| US-6500951-B1 | RING CLOSING A CARBOXYLIC ACID DERIVATIVE IN PRESENCE OF A NITROGEN CONTAINING AROMATIC COMPOUND AND A BORON COMPOUND; HIGH YIELD AND PURITY | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-12-31 | — | — | US | disclosed |