SCHEMBL8587206

SCHEMBL8587206

O=C1OB(c2cc(C(F)(F)F)cc(C(F)(F)F)c2)O[C@@H]1[C@H]1OB(c2cc(C(F)(F)F)cc(C(F)(F)F)c2)OC1=O

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.33
DDB1 Q16531 1/20 0.31
CRBN Q96SW2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10379650 0.80 CES2 (0.39) CES2
SCHEMBL6680366 0.71 CES2 (0.39) CES2
SCHEMBL14227199 0.69 TSHR (0.38) CES2
SCHEMBL6692161 0.66 CES2 (0.35) CES2
SCHEMBL14227219 0.66 CES2 (0.32) CES2
SCHEMBL18541476 0.64
SCHEMBL7784283 0.63 CES2 (0.33) CES2
SCHEMBL5077943 0.63 LPL (0.43) CES2
SCHEMBL10379432 0.62 CES2 (0.35) CES2
SCHEMBL440959 0.62 CES2 (0.58) CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-10251268-A None JP disclosed
JP-H10251268-A PRODUCTION OF OPTICALLY ACTIVE ALCOHOL COMPOUND TAKEDA CHEM IND LTD 1998-09-22 JP disclosed