Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGAV | P06756 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6680366 | 0.76 | CES2 (0.39) | CES2ITGB3ITGAVIDO1 | |
| SCHEMBL5077943 | 0.72 | LPL (0.43) | CES2 | |
| SCHEMBL6692161 | 0.71 | CES2 (0.35) | CES2IDO1 | |
| SCHEMBL10379650 | 0.69 | CES2 (0.39) | CES2IDO1 | |
| SCHEMBL13468810 | 0.67 | LPL (0.39) | — | |
| SCHEMBL14227219 | 0.67 | CES2 (0.32) | CES2 | |
| SCHEMBL14227199 | 0.67 | TSHR (0.38) | CES2IDO1 | |
| SCHEMBL440959 | 0.66 | CES2 (0.58) | CES2ITGB3ITGAVIDO1 | |
| SCHEMBL14994064 | 0.65 | FFAR1 (0.39) | CES2 | |
| SCHEMBL8587206 | 0.63 | CES2 (0.33) | CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1137641-A1 | PROCESS FOR PREPARING PYRIDAZIN-3-ON DERIVATIVES | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2001-10-04 | — | — | EP | disclosed |
| WO-2000034249-A1 | PROCESS FOR PREPARING PYRIDAZIN-3-ON DERIVATIVES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-06-15 | — | — | WO | disclosed |