SCHEMBL6681612

SCHEMBL6681612

CCN(CC)c1ccccc1C(c1ccccc1)c1ccccc1N(CC)CC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.41
SIGMAR1 Q99720 1/20 0.38
TSHR P16473 1/20 0.37
HRH1 P35367 4/20 0.36
HTR2A P28223 3/20 0.36
NR1H2 P55055 1/20 0.36
NR1H3 Q13133 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
AOC3 Q16853 3/20 0.35
CNR2 P34972 2/20 0.34
SLC6A3 Q01959 2/20 0.34
CACNA1F O60840 1/20 0.34
CHRM2 P08172 1/20 0.34
CHRM1 P11229 1/20 0.34
ADRA2B P18089 1/20 0.34
CHRM3 P20309 1/20 0.34
ADRA1A P35348 1/20 0.34
OPRK1 P41145 1/20 0.34
CACNA1D Q01668 1/20 0.34
KCNH2 Q12809 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3487781 0.90 TSHR (0.43) LMNATSHRNR1H2NR1H3AOC3
SCHEMBL30125051 0.88 TSHR (0.38) LMNATSHRTDP1AOC3CNR2
SCHEMBL1552804 0.88 TSHR (0.38) LMNATSHRTDP1AOC3CNR2
SCHEMBL9560020 0.81 MAPT (0.49) LMNASIGMAR1NR1H2NR1H3AOC3
SCHEMBL9724609 0.79 ESR1 (0.39) LMNATSHRHRH1HTR2ASLC6A3
SCHEMBL7901304 0.78 TSHR (0.38) LMNATSHRNR1H2NR1H3CNR2
SCHEMBL1778574 0.78 TSHR (0.48) LMNATSHRTDP1ADRA2BSMN1; SMN2
SCHEMBL9442819 0.78 HDAC6 (0.35) LMNATSHRCNR2CYP1A2CYP2D6
SCHEMBL29173184 0.78 GABRA1 (0.41) LMNATSHRCNR2SCN5ASLC6A2
SCHEMBL6247039 0.78 HTR2A (0.40) LMNATSHRHRH1HTR2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1251157-B1 Use of an adhesive comprising polyamide and electrically conductive filler for electrostatographic apparatuses XEROX CORP (US) 2004-11-17 EP claimed
JP-2003227549-A IMAGEABLE SEAMED BELT HAVING IMPROVED ADHESIVE WITH PLASTICIZER BETWEEN INTERLOCKING SEAMING MEMBERS XEROX CORP 2003-08-15 JP disclosed
EP-0270685-A1 PHOTOSENSITIVE MATERIAL FOR ELECTROPHOTOGRAPHY MITSUI TOATSU CHEMICALS, Inc. (JP) 1988-06-15 EP disclosed