Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1778574 | 0.90 | TSHR (0.48) | TSHRGABRA1GABRB2LMNAPOLB | |
| SCHEMBL6681612 | 0.90 | LMNA (0.41) | TSHRLMNANR1H2NR1H3MAPT | |
| SCHEMBL30326964 | 0.81 | CNR2 (0.47) | TSHRGABRA1GABRB2NR1H2NR1H3 | |
| SCHEMBL30125051 | 0.79 | TSHR (0.38) | TSHRLMNAALDH1A1MAPTCYP1A2 | |
| SCHEMBL1552804 | 0.79 | TSHR (0.38) | TSHRLMNAALDH1A1MAPTCYP1A2 | |
| SCHEMBL51106 | 0.79 | GABRA1 (0.52) | TSHRGABRA1GABRB2LMNAPOLB | |
| SCHEMBL9560020 | 0.77 | MAPT (0.49) | LMNANR1H2NR1H3ALDH1A1MAPT | |
| SCHEMBL982045 | 0.75 | GABRA1 (0.52) | TSHRGABRA1GABRB2LMNAPOLB | |
| SCHEMBL7901304 | 0.74 | TSHR (0.38) | TSHRLMNANR1H2NR1H3ALDH1A1 | |
| SCHEMBL10333062 | 0.73 | ALDH1A1 (0.42) | TSHRLMNAPOLBALOX15HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100047296-A1 | Low-Residue Cosmetic Or Dermatological Stick Based On An Oil-In-Water Dispersion/Emulsion III | HENKEL AG & CO. KGAA (DE) | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100047296-A1 | Low-Residue Cosmetic Or Dermatological Stick Based On An Oil-In-Water Dispersion/Emulsion III | TYR, POLR1C, CUTA | TSHR 1771/4885GABRA1 2490/4885GABRB2 2147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.