Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL133939 | 0.80 | TSHR (0.55) | TSHRKMT2AMAPTMEN1GAA | |
| SCHEMBL6681612 | 0.78 | LMNA (0.41) | TSHRKMT2AMAPTMEN1NR1H2 | |
| Hydrochloric Acid SCHEMBL11299552 | 0.78 | TSHR (0.53) | TSHRKMT2AMAPTMEN1GAA | |
| Hydrochloric Acid SCHEMBL10705984 | 0.77 | TSHR (0.52) | TSHRKMT2AMAPTMEN1GAA | |
| SCHEMBL7650155 | 0.74 | MAPT (0.61) | KMT2AMAPTMEN1GAAHTT | |
| SCHEMBL3487781 | 0.74 | TSHR (0.43) | TSHRKMT2AMAPTMEN1GAA | |
| Sulfuric Acid SCHEMBL9326021 | 0.72 | TSHR (0.47) | TSHRKMT2AMAPTMEN1GAA | |
| SCHEMBL11275342 | 0.72 | MAPT (0.65) | KMT2AMAPTMEN1GAAHTT | |
| SCHEMBL30125051 | 0.71 | TSHR (0.38) | TSHRKMT2AMAPTMEN1GAA | |
| SCHEMBL1552804 | 0.71 | TSHR (0.38) | TSHRKMT2AMAPTMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6187491-B1 | ELEMENT COMPRISING AN ELECTROCONDUCTIVE LAYER, PHOTOCONDUCTOR LAYER, PRIMER LAYER AND A SOLID POLYMER ELECTROLYTE LAYER COMPOSED OF A POLYSILSESQUIOXANE COMPLEXED WITH A CHARGE CARRIER AND INCLUDING AN ARYL TERTIARY AMINE | EASTMAN KODAK COMPANY | 2001-02-13 | — | — | US | disclosed |
| US-6066425-A | Electrophotographic charge generating element containing primer layer | EASTMAN KODAK COMPANY (US) | 2000-05-23 | — | — | US | disclosed |