Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.47 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.47 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.47 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.47 |
| ▸ | NQO1 | P15559 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6681989 | 0.85 | MAPT (0.55) | ERN1KDM4EMAPTCDK5CDK5R1 | |
| SCHEMBL6545110 | 0.85 | NQO1 (0.50) | ERN1KDM4EMAPTCDK5CDK5R1 | |
| SCHEMBL6544568 | 0.83 | ERN1 (0.63) | ERN1KDM4EMAPTCDK5CDK5R1 | |
| SCHEMBL5612804 | 0.83 | MAPT (0.55) | ERN1KDM4EMAPTCDK5CDK5R1 | |
| SCHEMBL2889415 | 0.82 | MAOA (0.58) | ERN1KDM4EMAPTCDK5CDK5R1 | |
| SCHEMBL20562674 | 0.81 | NQO1 (0.47) | ERN1KDM4EMAPTCDK5CDK5R1 | |
| SCHEMBL8817298 | 0.81 | ERN1 (0.61) | ERN1KDM4EPOLBPKMNQO1 | |
| SCHEMBL27423013 | 0.81 | MAOA (0.56) | ERN1KDM4EMAPTCDK5CDK5R1 | |
| SCHEMBL6345611 | 0.80 | ALDH1A1 (0.46) | ERN1KDM4EMAPTCDK5CDK5R1 | |
| SCHEMBL21718366 | 0.80 | NQO1 (0.46) | ERN1KDM4EMAPTCDK5CDK5R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042311-A1 | PHOTOCHROMIC 6-ARYL SUBSTITUTED 3H-NAPHTHO 2,1-b]PYRANS | TRANSITIONS OPTICAL, INC. (US) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999031082-A1 | PHOTOCHROMIC 6-ARYL SUBSTITUTED 3H-NAPHTHO[2,1-b]PYRANS | TRANSITIONS OPTICAL, INC. (US) | 1999-06-24 | — | — | WO | disclosed |