Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6676258 | 0.88 | CA1 (0.43) | MAPTCA1CA2MEN1KMT2A | |
| SCHEMBL7248116 | 0.87 | CA1 (0.43) | CA1CA2MEN1KMT2AATM | |
| SCHEMBL7247586 | 0.87 | CA1 (0.43) | MAPTCA1CA2MEN1KMT2A | |
| SCHEMBL6681999 | 0.83 | MAPT (0.45) | MAPTCA1CA2MEN1KMT2A | |
| SCHEMBL6675303 | 0.82 | NQO2 (0.40) | MAPTKMT2AALDH1A1 | |
| SCHEMBL6676112 | 0.82 | NAMPT (0.54) | CA1CA2KMT2ANAMPT | |
| SCHEMBL6688945 | 0.81 | CYP3A4 (0.46) | CA1CA2POLBNAMPT | |
| SCHEMBL6675049 | 0.80 | KMT2A (0.55) | MAPTCA1CA2MEN1KMT2A | |
| SCHEMBL7243630 | 0.80 | ALDH1A1 (0.42) | CA1CA2MEN1KMT2APOLB | |
| SCHEMBL6681934 | 0.80 | ALDH1A1 (0.42) | POLBALDH1A1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | disclosed |
| EP-0798292-A1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | Chugai Seiyaku Kabushiki Kaisha (JP) | 1997-10-01 | — | — | EP | disclosed |