Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6676262 | 0.88 | PTGER4 (0.41) | MAPTMEN1KMT2ACA1CA2 | |
| SCHEMBL7248121 | 0.87 | MEN1 (0.41) | MEN1KMT2AATMCA1CA2 | |
| SCHEMBL6675282 | 0.87 | NAMPT (0.40) | MAPTMEN1KMT2ACA1CA2 | |
| SCHEMBL6681996 | 0.83 | MAPT (0.46) | MAPTMEN1KMT2AATMCA12 | |
| SCHEMBL6675304 | 0.82 | MTNR1A (0.41) | MAPT | |
| SCHEMBL6676115 | 0.82 | NAMPT (0.53) | MAPTKMT2ACA1CA2NAMPT | |
| SCHEMBL6689914 | 0.80 | ALDH1A1 (0.41) | MEN1KMT2ANAMPTPOLBALDH1A1 | |
| SCHEMBL6675049 | 0.79 | KMT2A (0.55) | MAPTMEN1KMT2AATMCA12 | |
| SCHEMBL903446 | 0.77 | CA12 (0.64) | MAPTMEN1KMT2ACA12CA1 | |
| SCHEMBL31432851 | 0.77 | CA12 (0.64) | MAPTMEN1KMT2ACA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | disclosed |
| EP-0798292-A1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | Chugai Seiyaku Kabushiki Kaisha (JP) | 1997-10-01 | — | — | EP | disclosed |