SCHEMBL6681997

SCHEMBL6681997

CCCCCc1cc(Br)ccc1Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 1/20 0.41
HTT P42858 3/20 0.40
TYR P14679 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
TP53 P04637 1/20 0.40
CYP3A4 P08684 1/20 0.40
ALOX5 P09917 1/20 0.40
MAPT P10636 1/20 0.40
ALOX15 P16050 1/20 0.40
TSHR P16473 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
THRB P10828 1/20 0.39
HPGD P15428 1/20 0.39
BACE1 P56817 1/20 0.37
HTR2A P28223 1/20 0.37
SLC6A4 P31645 1/20 0.37
KCNH2 Q12809 1/20 0.37
LIPG Q9Y5X9 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26564798 0.86 PYCR1 (0.40) ABL1HTTTSHRTHRBHPGD
SCHEMBL27827947 0.81 TYR (0.50) HTTTYRMEN1KMT2ATP53
SCHEMBL6685016 0.81 TP53 (0.42) HTTTYRMEN1KMT2ATP53
SCHEMBL27878175 0.81 TYR (0.50) HTTTYRMEN1KMT2ATP53
SCHEMBL21175823 0.81 HPGD (0.46) MEN1KMT2ATDP1HPGDHTR2A
SCHEMBL2947274 0.79 TYR (0.44) HTTTYRMEN1KMT2ATP53
SCHEMBL1310459 0.79 TYR (0.44) ABL1HTTTYRMEN1KMT2A
SCHEMBL19846950 0.79 TYR (0.44) HTTTYRMEN1KMT2ATP53
SCHEMBL5180184 0.79 TYR (0.44) HTTTYRMEN1KMT2ATP53
SCHEMBL9503395 0.79 ALDH1A1 (0.42) HPGDHTR2ASLC6A4KCNH2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0985649-B1 Method for producing an aromatic compound having an alkyl group with at least three carbon atoms TORAY INDUSTRIES (JP) 2004-11-24 EP disclosed
US-6462248-B1 THROUGH CONVERSION, ISOMERIZATION AND/OR ADSORPTIVE SEPARATION OF AROMATIC COMPOUNDS TORAY INDUSTRIES, INC. (JP) 2002-10-08 US disclosed
EP-0985649-A2 Method for producing an aromatic compound having an alkyl group with at least three carbon atoms TORAY INDUSTRIES, INC. (JP) 2000-03-15 EP disclosed