Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.47 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.47 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 9/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29670238 | 1.00 | LIPG (0.55) | LIPGKEAP1PTGER1PTGER4PTGER3 | |
| SCHEMBL634254 | 0.87 | LIPG (0.64) | LIPGHDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL59198 | 0.81 | KEAP1 (0.65) | KEAP1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL3665652 | 0.80 | LIPG (0.50) | LIPGSMN1; SMN2 | |
| SCHEMBL2558811 | 0.80 | AKR1B1 (0.57) | LIPGADRA1A | |
| SCHEMBL878984 | 0.78 | KEAP1 (0.56) | KEAP1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL29670134 | 0.77 | LIPG (0.70) | LIPG | |
| SCHEMBL466443 | 0.77 | LIPG (0.70) | LIPG | |
| SCHEMBL18920823 | 0.77 | CYSLTR2 (0.55) | KEAP1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL323867 | 0.76 | NPSR1 (0.61) | KEAP1PTGER1PTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004056798-A1 | PHTHALAZINE DERIVATIVES PHOSPHODIESTERASE 4 INHIBITORS | ZAMBON GROUP S.P.A. (IT) | 2004-07-08 | — | — | WO | disclosed |