Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | CYSLTR2 | Q9NS75 | 6/20 | 0.51 |
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.51 |
| ▸ | F13A1 | P00488 | 3/20 | 0.49 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.48 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29670238 | 0.87 | LIPG (0.55) | LIPGHDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL6682047 | 0.87 | LIPG (0.55) | LIPGHDAC3MAPK1ADRA1AHDAC4 | |
| SCHEMBL22826566 | 0.83 | MAPT (0.67) | MAPTRXFP1CYSLTR2CYSLTR1F13A1 | |
| SCHEMBL15745852 | 0.83 | LIPG (0.88) | LIPG | |
| SCHEMBL25170031 | 0.81 | CYSLTR2 (0.68) | CYSLTR2CYSLTR1HDAC11 | |
| SCHEMBL27262058 | 0.81 | CYSLTR2 (0.68) | CYSLTR2CYSLTR1HDAC11 | |
| SCHEMBL12086495 | 0.81 | LTB4R (0.63) | MAPTRXFP1CYSLTR2CYSLTR1F13A1 | |
| SCHEMBL29670235 | 0.80 | LIPG (0.96) | LIPGCYSLTR2CYSLTR1 | |
| SCHEMBL747937 | 0.80 | LIPG (0.96) | LIPGCYSLTR2CYSLTR1 | |
| SCHEMBL22826567 | 0.80 | MAPT (0.62) | MAPTRXFP1CYSLTR2CYSLTR1F13A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2419478-B1 | FLUORESCENT IMAGING WITH SUBSTITUTED CYANINE DYES | LI COR INC (US) | 2018-02-28 | — | — | EP | disclosed |
| EP-2630196-B1 | CYANINE DYES AND THEIR CONJUGATES | LI COR INC (US) | 2017-09-06 | — | — | EP | disclosed |
| US-9408924-B2 | Bioconjugates of cyanine dyes | LI-COR, INC. (US) | 2016-08-09 | — | — | US | disclosed |
| US-20150119553-A1 | BIOCONJUGATES OF CYANINE DYES | LI-COR, INC. | 2015-04-30 | — | — | US | disclosed |
| US-8927719-B2 | Cyanine dyes and their conjugates | LI-COR, INC. (US) | 2015-01-06 | — | — | US | disclosed |
| US-20130274452-A1 | CYANINE DYES AND THEIR CONJUGATES | MIDCAP FINANCIAL TRUST | 2013-10-17 | — | — | US | disclosed |
| EP-2630196-A1 | CYANINE DYES AND THEIR CONJUGATES | LI-COR, INC. (US) | 2013-08-28 | — | — | EP | disclosed |
| US-8481752-B2 | Fluorescent imaging with substituted cyanine dyes | LI-COR, INC. (US) | 2013-07-09 | — | — | US | disclosed |
| WO-2012054749-A1 | CYANINE DYES AND THEIR CONJUGATES | LI-COR, INC. (US) | 2012-04-26 | — | — | WO | disclosed |
| EP-2419478-A2 | FLUORESCENT IMAGING WITH SUBSTITUTED CYANINE DYES | LI-COR, INC. (US) | 2012-02-22 | — | — | EP | disclosed |
| US-20100323389-A1 | FLUORESCENT IMAGING WITH SUBSTITUTED CYANINE DYES | LI-COR, INC. (US) | 2010-12-23 | — | — | US | disclosed |
| WO-2010121163-A2 | FLUORESCENT IMAGING WITH SUBSTITUTED CYANINE DYES | LI-COR, INC. (US) | 2010-10-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130274452-A1 | CYANINE DYES AND THEIR CONJUGATES | FCGR3B, QPCT, TIE1 | LIPG 2471/4885MAPT 2487/4885RXFP1 645/4885 |
| US-20100323389-A1 | FLUORESCENT IMAGING WITH SUBSTITUTED CYANINE DYES | MSR1, TIE1, ALG1 | LIPG 1862/4885MAPT 3260/4885RXFP1 419/4885 |
| US-20150119553-A1 | BIOCONJUGATES OF CYANINE DYES | FCGR3B, FCGR2A, HCCS | LIPG 2590/4885MAPT 3690/4885RXFP1 822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.