Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | CES2 | O00748 | 2/20 | 0.45 |
| ▸ | CES1 | P23141 | 2/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.45 |
| ▸ | MGLL | Q99685 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.36 |
| ▸ | CHRNG | P07510 | 1/20 | 0.36 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6682767 | 1.00 | GAA (0.54) | GAAMEN1KMT2ACES2CES1 | |
| SCHEMBL21509785 | 0.82 | CES2 (0.47) | GAAMEN1KMT2ACES2CES1 | |
| SCHEMBL13778625 | 0.81 | GAA (0.47) | GAAMEN1KMT2AMGLL | |
| SCHEMBL31114611 | 0.80 | GAA (0.42) | GAAMEN1KMT2ACES2CES1 | |
| SCHEMBL14383025 | 0.80 | TRPA1 (0.46) | GAAMEN1KMT2ACES2CES1 | |
| SCHEMBL2777130 | 0.78 | GAA (0.50) | GAAMEN1KMT2ACES2CES1 | |
| SCHEMBL2777133 | 0.78 | GAA (0.50) | GAAMEN1KMT2ACES2CES1 | |
| SCHEMBL15164589 | 0.76 | GAA (0.49) | GAAMEN1KMT2ACES2CES1 | |
| SCHEMBL8802041 | 0.75 | CES2 (0.52) | MEN1KMT2ACES2CES1TRPA1 | |
| SCHEMBL6179567 | 0.75 | MGLL (0.50) | CES2CES1MGLLRAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004064774-A2 | DNA ENCODING A HUMAN MELANIN CONCENTRATING HORMONE RECEPTOR (MCH1) AND USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 2004-08-05 | — | — | WO | disclosed |