Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.50 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.50 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | REN | P00797 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25378740 | 0.89 | LMNA (0.51) | LMNAKDM4EALDH1A1NPSR1TSHR | |
| SCHEMBL30482165 | 0.89 | TDP1 (0.49) | LMNAKDM4EALDH1A1NPSR1MEN1 | |
| SCHEMBL25376438 | 0.87 | TSHR (0.49) | LMNAKDM4EALDH1A1NPSR1TSHR | |
| SCHEMBL25378385 | 0.85 | KMT2A (0.58) | LMNAALDH1A1TSHRKMT2A | |
| Ammonia Solution, Strong SCHEMBL25374615 | 0.85 | TSHR (0.48) | LMNAKDM4EALDH1A1NPSR1TSHR | |
| SCHEMBL30482084 | 0.85 | KMT2A (0.58) | LMNAALDH1A1TSHRKMT2A | |
| SCHEMBL25378271 | 0.85 | TAS2R14 (0.47) | LMNAKDM4EALDH1A1NPSR1MEN1 | |
| SCHEMBL25376244 | 0.84 | GRIN2D (0.51) | LMNAKDM4EALDH1A1NPSR1GRIN2D | |
| SCHEMBL25375460 | 0.84 | L3MBTL1 (0.60) | LMNAALDH1A1NPSR1TSHRMEN1 | |
| SCHEMBL25375484 | 0.83 | HDAC1 (0.55) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024089225-A1 | PROCESS FOR THE SYNTHESIS OF METHOXY SUBSTITUTED BENZALDEHYDE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2024-05-02 | — | — | WO | claimed |
| CN-115872894-A | Synthesis of non-ionic contrast agents | 上海慧聚药业有限公司 | 2023-03-31 | — | — | CN | claimed |
| CN-114456135-A | Preparation of dronedarone | 江苏慧聚药业股份有限公司 | 2022-05-10 | — | — | CN | claimed |
| CN-113461572-A | Synthesis of 2- (3-bromo-5-methylphenyl) acetonitrile | 江苏慧聚药业有限公司 | 2021-10-01 | — | — | CN | claimed |
| CN-113444052-A | Synthesis of gefitinib | 江苏君若药业有限公司 | 2021-09-28 | — | — | CN | claimed |
| CN-111303131-B | Tegoprazan (Tegoprazan) analogue and synthetic method thereof | 江苏慧聚药业有限公司 | 2021-06-04 | — | — | CN | claimed |
| CN-111303131-A | Tegoprazan (Tegoprazan) analogue and synthetic method thereof | 海门慧聚药业有限公司 | 2020-06-19 | — | — | CN | claimed |
| US-20250136594-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. | 2025-05-01 | — | — | US | disclosed |
| CN-119080642-A | Non-neridrone key intermediate and preparation method thereof | 滁州市庆云医药有限公司 | 2024-12-06 | — | — | CN | disclosed |
| EP-4469438-A1 | COMPOUNDS AND METHODS OF USE | Tango Therapeutics, Inc. (US) | 2024-12-04 | — | — | EP | disclosed |
| WO-2024089225-A1 | PROCESS FOR THE SYNTHESIS OF METHOXY SUBSTITUTED BENZALDEHYDE COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2024-05-02 | — | — | WO | disclosed |
| US-20240067639-A1 | SMALL MOLECULES THAT TARGET THE RNA THAT CAUSES ALS | University of Florida Research Foundation, Incorporation (US) | 2024-02-29 | — | — | US | disclosed |
| CN-117504933-A | Hydroxy-substituted pyridine-2-carboxylic acid amide ligands and their use in copper catalyzed aryl halide coupling reactions | 中国科学院上海有机化学研究所 | 2024-02-06 | — | — | CN | disclosed |
| CN-113444052-A | Synthesis of gefitinib | 江苏君若药业有限公司 | 2021-09-28 | — | — | CN | disclosed |
| CN-111303131-B | Tegoprazan (Tegoprazan) analogue and synthetic method thereof | 江苏慧聚药业有限公司 | 2021-06-04 | — | — | CN | disclosed |
| CN-111303131-A | Tegoprazan (Tegoprazan) analogue and synthetic method thereof | 海门慧聚药业有限公司 | 2020-06-19 | — | — | CN | disclosed |
| CN-104151220-A | N,N'-dialkyl dithiooxamide as well as preparation method and application thereof | HUNAN CHEMAPI BIOLOG TECHNOLOGY CO LTD | 2014-11-19 | — | — | CN | disclosed |
| CN-1942448-A | Novel imidazoles | WARNER LAMBERT CO (US) | 2007-04-04 | — | — | CN | disclosed |
| WO-2004065305-A1 | NON-TOXIC CORROSION-PROTECTION PIGMENTS BASED ON MANGANESE | UNIVERSITY OF DAYTON (US) | 2004-08-05 | — | — | WO | disclosed |
| WO-2003060192-A1 | NON-TOXIC CORROSION-PROTECTION RINSES AND SEALS BASED ON COBALT | UNIVERSITY OF DAYTON (US) | 2003-07-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250136594-A1 | COMPOUNDS AND METHODS OF USE | CNKSR1, UGT1A1, REV1 | LMNA 936/4885KDM4E 1639/4885ALDH1A1 29/4885 |
| US-20240067639-A1 | SMALL MOLECULES THAT TARGET THE RNA THAT CAUSES ALS | FUS, SNRPE, RRBP1 | LMNA 1640/4885KDM4E 1687/4885ALDH1A1 4793/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.