Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.34 |
| ▸ | ACHE known ✓ | P22303 | 4/20 | 0.33 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALPG | P10696 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6682862 | 0.90 | ALDH1A1 (0.41) | ALDH1A1KDM4ETDP1MEN1KMT2A | |
| Succinic Acid SCHEMBL7270166 | 0.86 | BBOX1 (0.51) | BBOX1ALDH1A1KDM4ETDP1ALPL | |
| Acetic Acid SCHEMBL5720121 | 0.85 | ALDH1A1 (0.44) | BBOX1ALDH1A1KDM4ETDP1ALPL | |
| Bicarbonate SCHEMBL28038336 | 0.85 | ALDH1A1 (0.44) | BBOX1ALDH1A1KDM4ETDP1ALPL | |
| Bicarbonate SCHEMBL8962371 | 0.85 | ALDH1A1 (0.44) | BBOX1ALDH1A1KDM4ETDP1ALPL | |
| Bicarbonate SCHEMBL28038338 | 0.82 | ALDH1A1 (0.46) | BBOX1ALDH1A1KDM4ETDP1ALPL | |
| Hydrochloric Acid SCHEMBL11250018 | 0.80 | ALDH1A1 (0.54) | ALDH1A1KDM4ETDP1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL21638 | 0.80 | ALDH1A1 (0.54) | ALDH1A1KDM4ETDP1MEN1KMT2A | |
| Stearic Acid SCHEMBL28216815 | 0.80 | MEN1 (0.51) | BBOX1MEN1KMT2ASMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL11250021 | 0.79 | ALDH1A1 (0.52) | ALDH1A1KDM4ETDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040176262-A1 | Methods and compositions for drains and delivery lines | CLEAN CONTROL CORPORATION | 2004-09-09 | — | — | US | disclosed |
| WO-2004027007-A1 | METHODS AND COMPOSITIONS FOR DRAINS AND DELIVERY LINES | CLEAN CONTROL CORPORATION (US) | 2004-04-01 | — | — | WO | disclosed |