Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.38 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 5/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL5720121 | 0.92 | ALDH1A1 (0.44) | BBOX1ALDH1A1ALPLPOLBALPG | |
| Bicarbonate SCHEMBL8962371 | 0.92 | ALDH1A1 (0.44) | BBOX1ALDH1A1ALPLPOLBALPG | |
| Bicarbonate SCHEMBL28038336 | 0.92 | ALDH1A1 (0.44) | BBOX1ALDH1A1ALPLPOLBALPG | |
| Bicarbonate SCHEMBL28038338 | 0.89 | ALDH1A1 (0.46) | BBOX1ALDH1A1ALPLPOLBALPG | |
| Stearic Acid SCHEMBL28216815 | 0.87 | MEN1 (0.51) | BBOX1HDAC3HDAC4HDAC1HDAC7 | |
| Hydrochloric Acid SCHEMBL6682865 | 0.86 | BBOX1 (0.41) | BBOX1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9567755 | 0.85 | ALDH1A1 (0.40) | BBOX1ALDH1A1ALPLPOLBALPG | |
| SCHEMBL130071 | 0.85 | ALDH1A1 (0.50) | ALDH1A1ACHECHRM2CHRNA7KDM4E | |
| Mucic Acid SCHEMBL17534991 | 0.84 | ALPL (0.44) | BBOX1ALDH1A1ALPLPOLBALPG | |
| Fluoride Ion SCHEMBL6316238 | 0.84 | ALDH1A1 (0.48) | ALDH1A1ACHECHRM2CHRNA7KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4326977-A | Liquid antiseptic cleaners with improved foaming properties | BASF WYANDOTTE CORPORATION (US) | 1982-04-27 | — | — | US | claimed |
| US-6656919-B1 | Method and a product for the rapid decontamination and sterilization of bacterial endospores | BAUGH CLARENCE L (US) | 2003-12-02 | — | — | US | disclosed |
| WO-2000017303-A1 | ACIDIC HARD SURFACE CLEANING COMPOSITIONS | RECKITT BENCKISER INC. (US) | 2000-03-30 | — | — | WO | disclosed |
| US-4326977-A | Liquid antiseptic cleaners with improved foaming properties | BASF WYANDOTTE CORPORATION (US) | 1982-04-27 | — | — | US | disclosed |