Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 5/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SMO | Q99835 | 4/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6683560 | 0.82 | CTNNB1 (0.46) | SYKAURKBINCENPNPC1RAB9A | |
| SCHEMBL6501179 | 0.78 | SYK (0.47) | SYKNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL6663558 | 0.73 | EIF2AK3 (0.48) | SYKNPC1RAB9ALMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6670444 | 0.72 | EIF2AK3 (0.47) | SYKNPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL6795395 | 0.71 | SMO (0.59) | LMNASMO | |
| SCHEMBL30963267 | 0.71 | MAPT (0.48) | NPC1RAB9AFFAR1SMN1; SMN2MAPK14 | |
| SCHEMBL6923607 | 0.71 | THRB (0.51) | NPC1RAB9ALMNASMN1; SMN2MEN1 | |
| SCHEMBL6488813 | 0.70 | MAPT (0.47) | NPC1RAB9AMAPK14MEN1KMT2A | |
| SCHEMBL27683139 | 0.70 | RXRA (0.52) | SYKAURKBINCENPNPC1RAB9A | |
| SCHEMBL30963138 | 0.69 | KMT2A (0.53) | NPC1RAB9ALMNAHDAC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1472226-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003045921-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-06-05 | — | — | WO | disclosed |