Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | BACE1 | P56817 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 2/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL828713 | 0.86 | CHRM3 (0.51) | KMT2APKMALDH1A1CHRM3GPR119 | |
| SCHEMBL17205165 | 0.85 | TGFBR1 (0.57) | TGFBR1ACHEBACE1KMT2APKM | |
| SCHEMBL6667431 | 0.84 | ACHE (0.57) | ACHEBACE1KMT2APKMMAPK1 | |
| SCHEMBL24906656 | 0.84 | CHRM3 (0.70) | CHRM3 | |
| SCHEMBL829166 | 0.83 | NAMPT (0.45) | PKMALDH1A1CHRM3GPR119PTPN2 | |
| SCHEMBL29744615 | 0.82 | ALDH1A1 (0.63) | TGFBR1ACHEBACE1PKMMAPK1 | |
| SCHEMBL1673587 | 0.82 | ALDH1A1 (0.63) | TGFBR1ACHEBACE1PKMMAPK1 | |
| SCHEMBL13930893 | 0.82 | TGFBR1 (0.58) | TGFBR1ACHEBACE1KMT2APKM | |
| SCHEMBL19066214 | 0.81 | CHRM3 (0.48) | PKMCHRM3GPR119PTPN2PTPN1 | |
| SCHEMBL28685992 | 0.81 | ACHE (0.65) | TGFBR1ACHEBACE1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014425-A1 | ACTIVATORS OF SMALL CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNELS AND USE THEREOF | GLAXO GROUP LIMITED (GB) | 2004-02-19 | — | — | WO | disclosed |