Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 1/20 | 0.61 |
| ▸ | FEN1 | P39748 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 5/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | GSK3B | P49841 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.53 |
| ▸ | WNT3A | P56704 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2516127 | 0.87 | LMNA (0.75) | LMNARAB9ANPC1ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL3418541 | 0.86 | ERCC5 (0.57) | ERCC5FEN1LMNARAB9ANPC1 | |
| SCHEMBL668303 | 0.84 | LMNA (0.65) | ERCC5FEN1LMNARAB9ANPC1 | |
| SCHEMBL81392 | 0.84 | ALDH1A1 (0.62) | ERCC5FEN1LMNARAB9ANPC1 | |
| SCHEMBL711360 | 0.84 | RAB9A (0.75) | ERCC5FEN1LMNARAB9ANPC1 | |
| SCHEMBL5101292 | 0.83 | HPGD (0.69) | ERCC5FEN1LMNARAB9ANPC1 | |
| SCHEMBL9047740 | 0.83 | HPGD (0.69) | ERCC5FEN1LMNARAB9ANPC1 | |
| SCHEMBL1200691 | 0.83 | ALDH1A1 (0.58) | ERCC5FEN1LMNARAB9ANPC1 | |
| SCHEMBL1200128 | 0.83 | ERCC5 (0.54) | ERCC5FEN1LMNARAB9ANPC1 | |
| SCHEMBL20486436 | 0.82 | ERCC5 (0.67) | ERCC5FEN1LMNARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1405917-B1 | Process for the production of 3-Heteroaryl-3-hydroxy-propionic acid derivatives by enantioselective microbial reduction | SALTIGO GMBH (DE) | 2013-08-14 | — | — | EP | claimed |
| US-8293899-B2 | Ketone transfer hydrogenation of stereoisomerically enriched 3-heteroaryl-3-oxocarboxylic esters by reducing 3-heteroaryl-3-hydroxycarboxylic esters in the presence of a ruthenium-containing catalyst, an amine and formic acid and/or formates | LANXESS DEUTSCHLAND GMBH (DE) | 2012-10-23 | — | — | US | claimed |
| CN-1445224-B | Process for preparing arylaminopropanols | SALTIGO GMBH | 2012-07-11 | — | — | CN | claimed |
| EP-1346977-B1 | Method for producing aryl-aminopropanols | SALTIGO GMBH (DE) | 2009-07-22 | — | — | EP | claimed |
| CN-100510093-C | Method for preparing 3-heteroarylradical-3-hydroxy-propionic acid derivative | SALTIGO GMBH (DE) | 2009-07-08 | — | — | CN | claimed |
| US-20080262247-A1 | Process for preparing arylaminopropanols | ECKERT MARKUS | 2008-10-23 | — | — | US | claimed |
| EP-1340746-B1 | Process for the reduction of 3-heteroaryl-3-oxo-propanoic acid derivatives | SALTIGO GMBH (DE) | 2007-02-28 | — | — | EP | claimed |
| US-7169938-B2 | Process for preparing arylaminopropanols | LANXESS DEUTSCHLAND GMBH (DE) | 2007-01-30 | — | — | US | claimed |
| US-20040181058-A1 | Process for preparing 3-heteroaryl-3-hydroxypropanoic acid derivatives | LANXESS DEUTSCHLAND GMBH (DE) | 2004-09-16 | — | — | US | claimed |
| CN-1497048-A | Method for preparing 3-heteroarylradical-3-hydroxy-propionic acid derivative | 拜尔公司 | 2004-05-19 | — | — | CN | claimed |
| EP-1405917-A2 | Process for the production of 3-Heteroaryl-3-hydroxy-propionic acid derivatives by enantioselective microbial reduction | Bayer Chemicals AG (DE) | 2004-04-07 | — | — | EP | claimed |
| US-20030225153-A1 | Process for preparing arylaminopropanols | LANXESS DEUTSCHLAND GMBH (DE) | 2003-12-04 | — | — | US | claimed |
| US-20030225274-A1 | Process for reducing 3-heteroaryl-3-oxopropionic acid derivatives | LANXESS DEUTSCHLAND GMBH (DE) | 2003-12-04 | — | — | US | claimed |
| CN-1445224-A | Process for preparing arylaminopropanols | BAYER AG (DE) | 2003-10-01 | — | — | CN | claimed |
| EP-1340746-A1 | Process for the reduction of 3-heteroaryl-3-oxo-propanoic acid derivatives | BAYER AG (DE) | 2003-09-03 | — | — | EP | claimed |
| CN-117088824-A | Preparation method of alpha-1, 3, 5-triazine thioketone compound | 浙江工业大学 | 2023-11-21 | — | — | CN | disclosed |
| US-10431745-B2 | Diketopyrrolopyrrole polymers for use in organic field effect transistors | BASF SE (DE) | 2019-10-01 | — | — | US | disclosed |
| EP-1340746-A1 | Process for the reduction of 3-heteroaryl-3-oxo-propanoic acid derivatives | BAYER AG (DE) | 2003-09-03 | — | — | EP | disclosed |
| US-6215016-B1 | HEMATOPOIETIC AGENTS; PREVENTING CYTOPENIA | TORAY INDUSTRIES, INC. (JP) | 2001-04-10 | — | — | US | disclosed |
| EP-0841063-A1 | KETONE DERIVATIVES AND MEDICINAL USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1998-05-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030225153-A1 | Process for preparing arylaminopropanols | AHR, CYP1A1, CYP1A2 | ERCC5 2879/4885FEN1 1941/4885LMNA 2612/4885 |
| US-20040181058-A1 | Process for preparing 3-heteroaryl-3-hydroxypropanoic acid derivatives | HPD, HAAO, GRHPR | ERCC5 3209/4885FEN1 1511/4885LMNA 2210/4885 |
| US-20080262247-A1 | Process for preparing arylaminopropanols | CYP1A1, CYP1A2, AHR | ERCC5 2967/4885FEN1 1728/4885LMNA 2176/4885 |
| US-20030225274-A1 | Process for reducing 3-heteroaryl-3-oxopropionic acid derivatives | GRHPR, HPD, HAAO | ERCC5 1067/4885FEN1 1305/4885LMNA 3165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.