Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | BRD2 | P25440 | 1/20 | 0.30 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1734598 | 0.81 | MEN1 (0.35) | ALDH1A1MEN1KMT2A | |
| SCHEMBL2059594 | 0.79 | POLB (0.33) | MEN1KMT2A | |
| SCHEMBL5412420 | 0.79 | MEN1 (0.34) | ALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL28557476 | 0.78 | MYC (0.37) | ALDH1A1 | |
| SCHEMBL15968890 | 0.77 | ALDH1A1 (0.35) | ALDH1A1NPSR1CA2MEN1KMT2A | |
| SCHEMBL2057642 | 0.77 | MEN1 (0.30) | MEN1KMT2A | |
| SCHEMBL7758371 | 0.75 | KDM4E (0.38) | ALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL8773429 | 0.74 | POLB (0.33) | ALDH1A1 | |
| SCHEMBL7597928 | 0.74 | CASP1 (0.37) | ALDH1A1NPSR1CA2MEN1KMT2A | |
| SCHEMBL3744994 | 0.74 | CTDSP1 (0.33) | ALDH1A1NPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370547-B1 | BENZOAXATHIEPIN DERIVATIVES AND THEIR USE AS MEDICINES | PF MEDICAMENT (FR) | 2004-09-15 | — | — | EP | disclosed |
| EP-1370547-A1 | BENZOAXATHIEPIN DERIVATIVES AND THEIR USE AS MEDICINES | PIERRE FABRE MEDICAMENT (FR) | 2003-12-17 | — | — | EP | disclosed |
| WO-2002081464-A1 | BENZOAXATHIEPIN DERIVATIVES AND THEIR USE AS MEDICINES | PIERRE FABRE MEDICAMENT (FR) | 2002-10-17 | — | — | WO | disclosed |