Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.36 |
| ▸ | RXRA | P19793 | 3/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | MYC | P01106 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1734598 | 0.82 | MEN1 (0.35) | MAPTKMT2AMEN1GAAPOLB | |
| Ammonia Solution, Strong SCHEMBL28859729 | 0.81 | CASP1 (0.36) | CASP1SMN1; SMN2MYCMAOB | |
| SCHEMBL5412420 | 0.80 | MEN1 (0.34) | MAPTKMT2AMEN1GAAPOLB | |
| SCHEMBL8571190 | 0.77 | POLB (0.38) | CASP1MAPTKMT2AMEN1GAA | |
| SCHEMBL9258213 | 0.77 | LDHA (0.42) | MAPTKMT2AMEN1POLBSMN1; SMN2 | |
| SCHEMBL22444090 | 0.77 | MYC (0.40) | CASP1MAPTKMT2AMEN1GAA | |
| SCHEMBL28557476 | 0.76 | MYC (0.37) | CASP1MAPTGAAPOLBALDH1A1 | |
| Iodide SCHEMBL28419660 | 0.76 | MYC (0.39) | CASP1MAPTKMT2AMEN1GAA | |
| SCHEMBL6683040 | 0.74 | ALDH1A1 (0.32) | KMT2AMEN1ALDH1A1CA2NPSR1 | |
| SCHEMBL2057642 | 0.74 | MEN1 (0.30) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020143267-A1 | METABOLIC FITNESS TRAINING APPARATUS | GENERAL ELECTRIC CAPITAL CORPORATION | 2002-10-03 | — | — | US | disclosed |
| US-6454723-B1 | Metabolic fitness training apparatus | SUNBEAM PRODUCTS, INC. | 2002-09-24 | — | — | US | disclosed |