Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6683080 | 0.83 | TDP1 (0.56) | TDP1MAPTPTGS2MEN1KMT2A | |
| SCHEMBL6716560 | 0.74 | TDP1 (0.62) | TDP1MAPTPTGS2MEN1KMT2A | |
| SCHEMBL6713049 | 0.70 | TDP1 (0.58) | TDP1MAPTPTGS2MEN1KMT2A | |
| SCHEMBL1496356 | 0.69 | TRPV1 (0.59) | TDP1MAPTNPC1KDRABL1 | |
| SCHEMBL12225782 | 0.69 | NPC1 (0.69) | TDP1MAPTMEN1KMT2ANPC1 | |
| SCHEMBL18855245 | 0.68 | PTGS2 (0.52) | TDP1MAPTPTGS2MEN1KMT2A | |
| SCHEMBL4423725 | 0.68 | ALDH1A1 (0.52) | TDP1MAPTPTGS2MEN1KMT2A | |
| SCHEMBL1499586 | 0.67 | MAPT (0.61) | TDP1MAPTMEN1KMT2ANPC1 | |
| Triflumuron SCHEMBL29832813 | 0.67 | TDP1 (1.00) | TDP1MAPTMEN1KMT2ANPC1 | |
| Triflumuron SCHEMBL9490691 | 0.67 | TDP1 (1.00) | TDP1MAPTMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1427705-A2 | INSECTICIDAL DIAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2004-06-16 | — | — | EP | disclosed |
| WO-2003026415-A2 | INSECTICIDAL DIAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-04-03 | — | — | WO | disclosed |