Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 6/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 2/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16951581 | 0.83 | MGLL (0.38) | LMNACYP3A4MAPTKDM4EMEN1 | |
| SCHEMBL14659690 | 0.83 | CYP19A1 (0.46) | LMNACYP3A4MAPTKDM4EMEN1 | |
| SCHEMBL16954136 | 0.81 | LMNA (0.38) | LMNACYP3A4MAPTKDM4EMEN1 | |
| SCHEMBL16960695 | 0.80 | CYP4F2 (0.36) | LMNACYP3A4MAPTKDM4EMEN1 | |
| SCHEMBL6682154 | 0.78 | ALDH1A1 (0.41) | MGLLALDH1A1 | |
| SCHEMBL16951579 | 0.77 | MAPT (0.42) | LMNACYP3A4MAPTKDM4EMEN1 | |
| SCHEMBL6684044 | 0.77 | LMNA (0.49) | LMNACYP3A4MAPTKDM4EMEN1 | |
| SCHEMBL16951717 | 0.76 | LMNA (0.40) | LMNACYP3A4MAPTKDM4EMEN1 | |
| SCHEMBL16958807 | 0.76 | CYP19A1 (0.41) | LMNACYP3A4MAPTKDM4EMEN1 | |
| SCHEMBL1382104 | 0.74 | LMNA (0.44) | LMNACYP3A4MAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004063156-A1 | NOVEL INDOLE DERIVATES AS FABP-4 INHIBITORS | BIOVITRUM AB (SE) | 2004-07-29 | — | — | WO | disclosed |