Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL903695 | 0.84 | ALDH1A1 (0.58) | ALDH1A1ELANECYP1A1CYP1B1 | |
| SCHEMBL15958517 | 0.83 | ALDH1A1 (0.42) | ALDH1A1MGLLGRM5HPGDSKDM1A | |
| SCHEMBL202404 | 0.82 | ALDH1A1 (0.61) | ALDH1A1GRM5HPGDSKDM1APGR | |
| SCHEMBL3628529 | 0.81 | EPAS1 (0.41) | ALDH1A1MGLLGRM5HPGDSKDM1A | |
| SCHEMBL16961695 | 0.80 | ALDH1A1 (0.39) | ALDH1A1MGLLGRM5HPGDSKDM1A | |
| SCHEMBL509576 | 0.80 | ALDH1A1 (0.58) | ALDH1A1GRM5HPGDSKDM1APGR | |
| SCHEMBL21164288 | 0.79 | MGLL (0.38) | ALDH1A1MGLLGRM5HPGDSKDM1A | |
| SCHEMBL6683299 | 0.78 | LMNA (0.37) | ALDH1A1MGLL | |
| SCHEMBL21135650 | 0.77 | MGLL (0.40) | ALDH1A1MGLLGRM5HPGDSKDM1A | |
| SCHEMBL16959946 | 0.77 | ALDH1A1 (0.37) | ALDH1A1MGLLGRM5HPGDSKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004063156-A1 | NOVEL INDOLE DERIVATES AS FABP-4 INHIBITORS | BIOVITRUM AB (SE) | 2004-07-29 | — | — | WO | disclosed |