Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
| ▸ | PRCP | P42785 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5265951 | 0.84 | POLB (0.44) | POLBMEN1KMT2ASLC22A1PRCP | |
| SCHEMBL6961333 | 0.83 | POLB (0.39) | POLBMEN1KMT2A | |
| SCHEMBL7560334 | 0.81 | POLB (0.39) | POLBMEN1KMT2A | |
| SCHEMBL7444323 | 0.81 | POLB (0.41) | POLBMEN1KMT2A | |
| SCHEMBL6506502 | 0.79 | POLB (0.35) | POLBMEN1KMT2A | |
| SCHEMBL5543765 | 0.78 | POLB (0.39) | POLBMEN1KMT2A | |
| SCHEMBL7562738 | 0.77 | POLB (0.36) | POLBMEN1KMT2A | |
| SCHEMBL6504166 | 0.77 | POLB (0.34) | POLBMEN1KMT2A | |
| SCHEMBL7561336 | 0.75 | MEN1 (0.41) | MEN1KMT2A | |
| SCHEMBL7844747 | 0.74 | CDK9 (0.35) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004064774-A2 | DNA ENCODING A HUMAN MELANIN CONCENTRATING HORMONE RECEPTOR (MCH1) AND USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 2004-08-05 | — | — | WO | disclosed |