Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5265951 | 0.86 | POLB (0.44) | POLBMEN1KMT2A | |
| SCHEMBL7444323 | 0.85 | POLB (0.41) | POLBSMN1; SMN2MEN1MAPTKMT2A | |
| SCHEMBL7432997 | 0.81 | SIGMAR1 (0.41) | SLC6A2SMN1; SMN2MAPTKMT2ALMNA | |
| SCHEMBL7435086 | 0.81 | HTR2C (0.49) | SLC6A2HRH1HRH4MAOB | |
| SCHEMBL6683579 | 0.77 | POLB (0.37) | POLBMEN1KMT2A | |
| SCHEMBL6961333 | 0.77 | POLB (0.39) | POLBMEN1KMT2A | |
| SCHEMBL5543765 | 0.77 | POLB (0.39) | POLBMEN1KMT2AMAOB | |
| SCHEMBL8370371 | 0.76 | ESR2 (0.43) | — | |
| SCHEMBL8371294 | 0.76 | CYP2A6 (0.35) | POLBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL4789903 | 0.76 | ADRA2A (0.41) | HRH1HRH4IDO1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002076440-A2 | METHODS OF TREATING ALZHEIMER'S DISEASE WITH PIPERIDIN DERIVATES | ELAN PHARMACEUTICALS, INC. (US) | 2002-10-03 | — | — | WO | disclosed |