Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6504166 | 0.84 | POLB (0.34) | POLBMEN1KMT2A | |
| SCHEMBL7399937 | 0.82 | NISCH (0.31) | — | |
| SCHEMBL8368017 | 0.81 | SLC6A3 (0.37) | POLBMEN1KMT2A | |
| SCHEMBL6683579 | 0.81 | POLB (0.37) | POLBMEN1KMT2A | |
| SCHEMBL5265951 | 0.80 | POLB (0.44) | POLBMEN1KMT2A | |
| SCHEMBL6961333 | 0.80 | POLB (0.39) | POLBMEN1KMT2A | |
| SCHEMBL7844747 | 0.79 | CDK9 (0.35) | POLB | |
| SCHEMBL6506502 | 0.79 | POLB (0.35) | POLBMEN1KMT2A | |
| SCHEMBL8312119 | 0.75 | POLB (0.40) | POLBMEN1KMT2A | |
| SCHEMBL4788776 | 0.75 | IDH1 (0.36) | POLBIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002076440-A2 | METHODS OF TREATING ALZHEIMER'S DISEASE WITH PIPERIDIN DERIVATES | ELAN PHARMACEUTICALS, INC. (US) | 2002-10-03 | — | — | WO | disclosed |