Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6683871 | 0.78 | HTR6 (0.37) | SIGMAR1 | |
| SCHEMBL6905039 | 0.74 | MALT1 (0.38) | SIGMAR1 | |
| SCHEMBL6906313 | 0.71 | CES1 (0.45) | — | |
| SCHEMBL28220073 | 0.69 | HTR6 (0.53) | TAAR1SIGMAR1 | |
| Demelverine SCHEMBL1516521 | 0.69 | SIGMAR1 (0.76) | TAAR1AOC3SIGMAR1 | |
| SCHEMBL6542721 | 0.68 | TAAR1 (0.64) | TAAR1AOC3SIGMAR1 | |
| SCHEMBL9768687 | 0.67 | SIGMAR1 (0.73) | TAAR1AOC3SIGMAR1 | |
| Hydrochloric Acid SCHEMBL27476339 | 0.66 | TAAR1 (0.61) | TAAR1AOC3SIGMAR1 | |
| SCHEMBL168948 | 0.65 | TAAR1 (1.00) | TAAR1AOC3SIGMAR1 | |
| SCHEMBL22863888 | 0.65 | TAAR1 (1.00) | TAAR1AOC3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1359916-A4 | IMIDAZOLYL DERIVATIVES AS CORTICOTROPIN RELEASING FACTOR INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2004-04-07 | — | — | EP | disclosed |
| EP-1359916-A1 | IMIDAZOLYL DERIVATIVES AS CORTICOTROPIN RELEASING FACTOR INHIBITORS | Bristol-Myers Squibb Company (US) | 2003-11-12 | — | — | EP | disclosed |
| WO-2002058704-A1 | IMIDAZOLYL DERIVATIVES AS CORTICOTROPIN RELEASING FACTOR INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-08-01 | — | — | WO | disclosed |