SCHEMBL6683893

SCHEMBL6683893

C=CC[Si](C)(C)Cl.C=CCc1ccccc1[SiH](Cl)Cl

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.34
GABRB2 P47870 1/20 0.34
ADRA2B P18089 6/20 0.31
ADRA2C P18825 6/20 0.31
ADRA2A P08913 5/20 0.31
HTR1A P08908 3/20 0.31
KCNH2 Q12809 1/20 0.31
ALDH1A1 P00352 1/20 0.31
NISCH Q9Y2I1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL125206 0.87 GABRA1 (0.42) GABRA1GABRB2ADRA2BADRA2CADRA2A
SCHEMBL5696529 0.73 ALDH1A1 (0.30) ALDH1A1
SCHEMBL28730875 0.72 GABRA1 (0.42) GABRA1GABRB2ADRA2BADRA2CADRA2A
SCHEMBL3772407 0.69 GABRA1 (0.40) GABRA1GABRB2ADRA2BADRA2CADRA2A
SCHEMBL28730873 0.69 GABRA1 (0.40) GABRA1GABRB2ADRA2BADRA2CADRA2A
SCHEMBL6841674 0.69 GABRA1 (0.47) GABRA1GABRB2ADRA2CHTR1AKCNH2
SCHEMBL123281 0.69
SCHEMBL3109867 0.68 GABRA1 (0.39) GABRA1GABRB2ADRA2BADRA2CADRA2A
SCHEMBL5512042 0.68 NR1H2 (0.33)
SCHEMBL173300 0.66 GABRA1 (0.56) GABRA1GABRB2ADRA2BADRA2CADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6703176-B2 MIXTURE OF BONDING POLYMER AND COLORING AGENT; MELT KNEADING CANON KABUSHIKI KAISHA (JP) 2004-03-09 US disclosed