Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HK1 | P19367 | 1/20 | 0.41 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8210753 | 0.85 | ALDH1A1 (0.41) | MEN1KMT2ARAB9AALDH1A1MAOB | |
| SCHEMBL9649780 | 0.85 | GABRP (0.42) | MEN1KMT2ARAB9AALDH1A1MAOB | |
| SCHEMBL28157175 | 0.85 | ALDH1A1 (0.44) | MEN1KMT2ARAB9AALDH1A1MAOB | |
| SCHEMBL8506859 | 0.85 | GABRP (0.42) | MEN1KMT2ARAB9AALDH1A1MAOB | |
| SCHEMBL11074877 | 0.82 | ALDH1A1 (0.48) | MEN1KMT2ARAB9AALDH1A1MAOB | |
| SCHEMBL27825751 | 0.82 | MAOB (0.43) | MEN1KMT2ARAB9AALDH1A1MAOB | |
| SCHEMBL7101700 | 0.81 | MAOB (0.42) | MEN1KMT2ARAB9AMAOBHPGD | |
| SCHEMBL27947263 | 0.80 | MAOB (0.42) | MEN1KMT2ARAB9AALDH1A1MAOB | |
| SCHEMBL7222379 | 0.80 | RAB9A (0.44) | MEN1KMT2ARAB9AALDH1A1MAOB | |
| SCHEMBL15066583 | 0.79 | CYP2A6 (0.32) | ALDH1A1ALOX15MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016049677-A1 | METHOD OF TREATING CANCER | THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH (AU) | 2016-04-07 | — | — | WO | disclosed |
| WO-2004065350-A1 | TERTIARY AMINO ACIDS, THEIR PRODUCTION AND USE | MEDIGENE AKTIENGESELLSCHAFT (DE) | 2004-08-05 | — | — | WO | disclosed |
| EP-0525573-A1 | Organogermanium and organosilicon compounds, process for the preparation of the same and use thereof | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1993-02-03 | — | — | EP | disclosed |