SCHEMBL27825751

SCHEMBL27825751

Brc1cccc(-c2[c]cccc2)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 4/20 0.43
MAOA P21397 1/20 0.43
RAB9A P51151 4/20 0.42
NPC1 O15118 3/20 0.42
TSHR P16473 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
TP53 P04637 1/20 0.42
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
GABRA1 P14867 3/20 0.39
GABRG2 P18507 3/20 0.39
GABRB3 P28472 3/20 0.39
GABRA5 P31644 3/20 0.39
GABRA3 P34903 3/20 0.39
GABRP O00591 2/20 0.39
GABRD O14764 2/20 0.39
GABRB1 P18505 2/20 0.39
GABRA2 P47869 2/20 0.39
GABRB2 P47870 2/20 0.39
GABRA4 P48169 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27947263 0.98 MAOB (0.42) MAOBMAOARAB9ANPC1TSHR
SCHEMBL27574065 0.91 MAOA (0.40) MAOBMAOARAB9ANPC1TSHR
SCHEMBL17046416 0.83 ALDH1A1 (0.31) MAOBMAOAALDH1A1
SCHEMBL6683909 0.82 MEN1 (0.42) MAOBMAOARAB9ANPC1TSHR
SCHEMBL183516 0.80 ALDH1A1 (0.35) RAB9AMEN1KMT2AALDH1A1
SCHEMBL26567 0.79 MAOA (0.41) MAOAMEN1KMT2AALDH1A1HTT
SCHEMBL589437 0.79 MAOA (0.41) MAOAMEN1KMT2AALDH1A1HTT
SCHEMBL4585973 0.77 ALDH1A1 (0.48) MAOBRAB9ANPC1TSHRSMN1; SMN2
SCHEMBL2115007 0.76 NPC1 (0.42) MAOBRAB9ANPC1TSHRSMN1; SMN2
SCHEMBL2115058 0.76 ACHE (0.42) RAB9ANPC1TSHRSMN1; SMN2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110452689-A Triazolopyridine-based organic electroluminescent material and organic electroluminescent device WUHAN SUNSHINE OPTOELECTRONICS TECH CO LTD 2019-11-15 CN disclosed
CN-106518634-B A kind of preparation method of photocatalysis α-dione compounds 大连理工大学 2019-03-05 CN disclosed
CN-107001292-A Organic photovoltaic component compound and organic photovoltaic component and display element 三星SDI株式会社 2017-08-01 CN disclosed
CN-106518634-A Preparing method of photocatalytic alpha-diketone compound 大连理工大学 2017-03-22 CN disclosed
CN-106083835-A Heterocyclic compound, light-emitting component, luminescent device, electronic device and illuminating device 株式会社半导体能源研究所 2016-11-09 CN disclosed
CN-102190653-B Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device 株式会社半导体能源研究所 2016-07-13 CN disclosed
CN-103030632-B Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LAB 2014-12-17 CN disclosed
CN-103030632-A Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LAB 2013-04-10 CN disclosed
CN-102190653-A Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LAB 2011-09-21 CN disclosed