Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.69 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.69 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.60 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.51 |
| ▸ | HTR3B | O95264 | 2/20 | 0.51 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.51 |
| ▸ | CHRNG | P07510 | 2/20 | 0.51 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.51 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27851449 | 0.98 | NR4A2 (0.67) | NR4A2CREBBPPBRM1GPR84ALDH1A1 | |
| SCHEMBL1093530 | 0.81 | NR4A2 (1.00) | NR4A2CREBBPPBRM1GPR84ALDH1A1 | |
| SCHEMBL30031033 | 0.81 | NR4A2 (1.00) | NR4A2CREBBPPBRM1GPR84ALDH1A1 | |
| SCHEMBL5163293 | 0.81 | LMNA (0.57) | NR4A2CREBBPPBRM1GPR84KMT2A | |
| SCHEMBL27664022 | 0.81 | PBRM1 (0.51) | NR4A2CREBBPPBRM1GPR84ALDH1A1 | |
| SCHEMBL6991795 | 0.80 | NR4A2 (0.51) | NR4A2CREBBPALDH1A1LMNANPSR1 | |
| SCHEMBL1696922 | 0.80 | NR4A2 (0.51) | NR4A2CREBBPMAPTHTR3EHTR3B | |
| Hydrochloric Acid SCHEMBL28254334 | 0.80 | NR4A2 (0.97) | NR4A2CREBBPPBRM1GPR84ALDH1A1 | |
| SCHEMBL3995918 | 0.80 | NR4A2 (0.55) | NR4A2CREBBPPBRM1GPR84ALDH1A1 | |
| SCHEMBL10780508 | 0.80 | NPC1 (0.57) | NR4A2CREBBPPBRM1GPR84ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715167-A | Lipid-substituted amino 1, 2-and 1, 3-diol compounds as modulators of TLR2 dimerization | 神经孔疗法股份有限公司 | 2019-05-03 | — | — | CN | claimed |
| CN-103570688-A | 2,5-diaminomethylpyrazine compounds, drug compositions, preparation method and use thereof | SHANGHAI INST MATERIA MEDICA | 2014-02-12 | — | — | CN | claimed |
| CN-112239468-B | Metal-free solvent-free synthesis of fused pyridine heterocycles and biomedical applications thereof | 印多尔印度理工学院 | 2025-05-27 | — | — | CN | disclosed |
| EP-4265621-A1 | PYRROLE DERIVATIVE, AND PREPARATION METHOD AND USE THEREFOR | Shenzhen Sungening Bio-Medical Co., Ltd. (CN) | 2023-10-25 | — | — | EP | disclosed |
| WO-2022237813-A1 | COMPOUND HAVING ALK INHIBITORY ACTIVITY, PREPARATION METHOD THEREFOR AND USE THEREOF | 盛世泰科生物医药技术(苏州)有限公司 | 2022-11-17 | — | — | WO | disclosed |
| CN-114616224-A | Novel tricyclic 5-HT2Antagonists | 安娜玛有限公司 | 2022-06-10 | — | — | CN | disclosed |
| US-20220119378-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2022-04-21 | — | — | US | disclosed |
| US-20220119378-A1 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. | 2022-04-21 | — | — | US | disclosed |
| CN-114106185-A | anti-HER 2 antibodies and immunoconjugates | 基因泰克公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-107001479-B | anti-HER 2 antibodies and immunoconjugates | 基因泰克公司 | 2021-09-28 | — | — | CN | disclosed |
| CN-109328059-B | Selective inhibitors of clinically important mutants of EGFR tyrosine kinase | CS制药技术有限公司 | 2021-08-17 | — | — | CN | disclosed |
| CN-1950374-A | Tetraazabenzo[e]azulene derivatives and analogs thereof | PFIZER (US) | 2007-04-18 | — | — | CN | disclosed |
| CN-1914207-A | Aza * -indoline derivatives as medicaments | EXELIXIS INC (US) | 2007-02-14 | — | — | CN | disclosed |
| CN-1894264-A | Organophosphorous indazole derivatives and use thereof as protein kinase inhibitors | AVENTIS PHARMA SA (FR) | 2007-01-10 | — | — | CN | disclosed |
| WO-2004063336-A2 | USES OF DEAZAPURINES FOR THE TREATMENT OF REPERFUSION INJURIES, OSTEOPOROSIS AND/OR BONE METASTASIS | EISAI CO. LTD. (JP) | 2004-07-29 | — | — | WO | disclosed |
| CN-1418216-A | Novel 2,3,4, 5-tetrahydro-1H- [1,4] diaza * o [1, 7-a ] indole compounds | UPJOHN CO (US) | 2003-05-14 | — | — | CN | disclosed |
| CN-1370176-A | Subsstituted heterocycle fused gamma-carbolines | BRISTOL MYERS SQUIBB CO (US) | 2002-09-18 | — | — | CN | disclosed |
| CN-1208413-A | Gonadotropin releasing hormone antagonists | MERCK & CO INC (US) | 1999-02-17 | — | — | CN | disclosed |
| US-5760032-A | GASTROINTESTINAL DISORDERS AND NERVOUS SYSTEM DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-06-02 | — | — | US | disclosed |
| EP-0776892-A1 | THIENYLAZOLE COMPOUND AND THIENOTRIAZOLODIAZEPINE COMPOUND | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1997-06-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220119378-A1 | COMPOUNDS AND USES THEREOF | VHL, CLN6, TFEB | NR4A2 2024/4885CREBBP 607/4885PBRM1 18/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.