SCHEMBL668443

SCHEMBL668443

CC(=O)C=C(O)c1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 1/20 0.64
CA12 O43570 2/20 0.61
CA1 P00915 2/20 0.61
CA2 P00918 2/20 0.61
CA9 Q16790 2/20 0.61
CYP3A4 P08684 2/20 0.52
MAPT P10636 2/20 0.52
KDM4E B2RXH2 1/20 0.52
HPGD P15428 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
CES2 O00748 3/20 0.50
CES1 P23141 3/20 0.50
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
NPC1 O15118 1/20 0.48
GAA P10253 1/20 0.48
RAB9A P51151 1/20 0.48
TSHR P16473 3/20 0.46
ALDH1A1 P00352 2/20 0.46
DAO P14920 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11498687 1.00 NFE2L2 (0.64) NFE2L2CA12CA1CA2CA9
SCHEMBL10304521 1.00 NFE2L2 (0.64) NFE2L2CA12CA1CA2CA9
SCHEMBL15454973 0.98 NFE2L2 (0.61) NFE2L2CA12CA1CA2CA9
SCHEMBL15454975 0.98 NFE2L2 (0.61) NFE2L2CA12CA1CA2CA9
SCHEMBL4449994 0.84 NFE2L2 (0.50) NFE2L2CA12CA1CA2CA9
SCHEMBL26147588 0.82 ALDH1A1 (0.59) NFE2L2MAPTKDM4EHPGDSMN1; SMN2
SCHEMBL26163201 0.82 CA12 (0.50) NFE2L2CA12CA1CA2CA9
SCHEMBL566351 0.81 DEGS1 (0.53) NFE2L2CA12CA1CA2CA9
SCHEMBL566350 0.81 DEGS1 (0.53) NFE2L2CA12CA1CA2CA9
SCHEMBL4863098 0.81 CES2 (0.50) NFE2L2CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250033082-A1 METHOD AND COMPOSITION FOR REDUCING SOLVENT RELEASE FROM, AND REDUCING ODOR OF, AGROCHEMICAL FORMULATIONS ADAMA MAKHTESHIM LTD. (IL) 2025-01-30 US claimed
EP-4423178-A1 METHOD AND COMPOSITION FOR REDUCING SOLVENT RELEASE FROM, AND REDUCING ODOR OF, AGROCHEMICAL FORMULATIONS ADAMA MAKHTESHIM LTD. (IL) 2024-09-04 EP claimed
CN-118201991-A Methods and compositions for reducing solvent release from agrochemical formulations and reducing agrochemical formulation odor 安道麦马克西姆有限公司 2024-06-14 CN claimed
EP-4259812-A1 METHOD FOR THE PREPARATION OF FRAMBINONE SPECIALTY OPERATIONS FRANCE (FR) 2023-10-18 EP claimed
WO-2023073536-A1 METHOD AND COMPOSITION FOR REDUCING SOLVENT RELEASE FROM, AND REDUCING ODOR OF, AGROCHEMICAL FORMULATIONS ADAMA MAKHTESHIM LTD. (IL) 2023-05-04 WO claimed
WO-2022129012-A1 METHOD FOR THE PREPARATION OF FRAMBINONE RHODIA OPERATIONS (FR) 2022-06-23 WO claimed
CN-103923061-A Heterocyclic 1,4-pentadiene-3-ketoxime compound as well as preparation method and application thereof UNIV GUIZHOU 2014-07-16 CN claimed
CN-103896865-A 1,4-pentadiene-3-ketone compounds containing triazole amide and preparation method and application thereof XINGYI NORMAL UNIVERSITY FOR NATIONALITIES 2014-07-02 CN claimed
US-20250327100-A1 Strain of Pseudomonas Putida Genetically Modified to Express a Benzalacetone Reductase BGENE GENETICS (FR) 2025-10-23 US disclosed
US-20250171750-A1 Modified Polyketide Synthase Enzymes and Uses Thereof BGENE GENETICS (FR) 2025-05-29 US disclosed
EP-4560015-A2 MODIFIED POLYKETIDE SYNTHASE ENZYMES AND USES THEREOF BGene Genetics (FR) 2025-05-28 EP disclosed
EP-4370674-A1 STRAIN OF PSEUDOMONAS PUTIDA GENETICALLY MODIFIED TO EXPRESS A BENZALACETONE REDUCTASE BGene Genetics (FR) 2024-05-22 EP disclosed
WO-2023230574-A1 ENGINEERED PHENYLALANINE AMMONIA LYASE AND TYROSINE AMMONIA LYASE ENZYMES FOR PRODUCING AROMATIC COMPOUNDS GINKGO BIOWORKS, INC. (US) 2023-11-30 WO disclosed
EP-4259812-A1 METHOD FOR THE PREPARATION OF FRAMBINONE SPECIALTY OPERATIONS FRANCE (FR) 2023-10-18 EP disclosed
EP-2689020-A1 MICROBIAL PRODUCTION OF CHEMICAL PRODUCTS AND RELATED COMPOSITIONS, METHODS AND SYSTEMS OPX Biotechnologies Inc. (US) 2014-01-29 EP disclosed
US-20130122541-A1 MICROORGANISM PRODUCTION OF HIGH-VALUE CHEMICAL PRODUCTS, AND RELATED COMPOSITIONS, METHODS AND SYSTEMS THE REGENTS OF THE UNIVERSITY OF COLORADO 2013-05-16 US disclosed
WO-2012129450-A1 MICROBIAL PRODUCTION OF CHEMICAL PRODUCTS AND RELATED COMPOSITIONS, METHODS AND SYSTEMS OPX BIOTECHNOLOGIES, INC. (US) 2012-09-27 WO disclosed
US-20120046247-A1 1,5-DIPHENYL-PENTA-1,4-DIEN-3-ONE COMPOUNDS ALLIANZ PHARMASCIENCE LTD. (TW) 2012-02-23 US disclosed
US-5951841-A ACIDIC ELECTROPLATING BATHS COMPRISING BRIGHTENERS FOR THE ELECTROLYTIC DEPOSITION OF METALLIC INORGANIC LAYERS ONTO SHAPED ARTICLES BASF AKTIENGESELLSCHAFT (DE) 1999-09-14 US disclosed
US-4182861-A OPTICAL BRIGHTENERS FOR POLYESTER, COTTON, POLYAMIDE AND POLYACRYLONITRILE FABRICS, POLYVINYL CHLORIDE FOILS SANDOZ LTD. (CH) 1980-01-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120046247-A1 1,5-DIPHENYL-PENTA-1,4-DIEN-3-ONE COMPOUNDS PDCD5, IL5, MALT1 NFE2L2 957/4885CA12 2222/4885CA1 1589/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.