Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 5/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6687191 | 0.85 | CDC25C (0.54) | CHRM2ALDH1A1TAAR1CYP19A1CA12 | |
| SCHEMBL6549530 | 0.81 | TDP1 (0.50) | ALDH1A1CYP19A1CYP3A4TDP1HTT | |
| SCHEMBL11783489 | 0.80 | KCNH2 (0.49) | ALDH1A1CYP19A1CYP3A4TDP1HTT | |
| SCHEMBL3477025 | 0.80 | KCNH2 (0.49) | ALDH1A1CYP19A1CYP3A4TDP1HTT | |
| SCHEMBL6688354 | 0.80 | ALDH1A1 (0.53) | ALDH1A1TAAR1CYP19A1MGLLTBXA2R | |
| SCHEMBL7921397 | 0.79 | TDP1 (0.51) | ALDH1A1CYP19A1CYP3A4TDP1HTT | |
| SCHEMBL6272594 | 0.79 | HRH4 (0.46) | CHRM2ALDH1A1CA12CA2CA9 | |
| Hydrochloric Acid SCHEMBL6685629 | 0.78 | CYP1A2 (0.45) | CHRM2ALDH1A1TDP1POLBTSHR | |
| Hydrochloric Acid SCHEMBL6270325 | 0.78 | CYP1A2 (0.45) | CHRM2ALDH1A1TDP1POLBTSHR | |
| SCHEMBL460989 | 0.77 | HTT (0.66) | ALDH1A1CYP3A4TDP1HTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1310479-B1 | Process for the preparation of 2-aminomethyl-1,4-diamino-benzene and salts thereof | WELLA AG (DE) | 2004-10-27 | — | — | EP | claimed |
| EP-1310479-B1 | Process for the preparation of 2-aminomethyl-1,4-diamino-benzene and salts thereof | WELLA AG (DE) | 2004-10-27 | — | — | EP | disclosed |
| EP-1310479-A1 | Process for the preparation of 2-aminomethyl-1,4-diamino-benzene and salts thereof | Wella Aktiengesellschaft (DE) | 2003-05-14 | — | — | EP | disclosed |
| US-6461390-B1 | Process for making 2-aminomethyl-1, 4-diaminobenzene and its salts and compositions and methods for dyeing keratin fibers using same | WELLA AKTIENGESELLSCHAFT (DE) | 2002-10-08 | — | — | US | disclosed |
| US-6461390-B1 | Process for making 2-aminomethyl-1, 4-diaminobenzene and its salts and compositions and methods for dyeing keratin fibers using same | WELLA AKTIENGESELLSCHAFT (DE) | 2002-10-08 | — | — | US | disclosed |
| EP-1110942-A2 | Process for the preparation of 2-aminomethyl-1,4-diamino-benzene and salts thereof, and their use in dyeing composition for keratin fibers | Wella Aktiengesellschaft (DE) | 2001-06-27 | — | — | EP | disclosed |
| JP-2001172231-A | METHOD FOR PRODUCING 2-AMINOMETHYL-1,4-DIAMINO-BENZENE AND ITS SALT AND USE OF THESE COMPOUNDS AS DYEING AGENT FOR KERATIN FIBER | WELLA AG | 2001-06-26 | — | — | JP | disclosed |