Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25C | P30307 | 1/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.43 |
| ▸ | ITGB7 | P26010 | 3/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6684448 | 0.85 | CHRM2 (0.49) | CHRM2MGLLALDH1A1TAAR1CYP19A1 | |
| SCHEMBL6412685 | 0.84 | CDC25C (0.53) | CDC25CAPPMEN1CRHBPKMT2A | |
| SCHEMBL11509750 | 0.84 | APP (0.56) | CDC25CAPPMEN1CRHBPKMT2A | |
| SCHEMBL9827648 | 0.82 | CDC25C (0.55) | CDC25CAPPMEN1CRHBPKMT2A | |
| SCHEMBL899648 | 0.81 | ALDH1A1 (0.50) | MEN1KMT2AALDH1A1ERN1CTSB | |
| SCHEMBL899647 | 0.81 | ALDH1A1 (0.50) | MEN1KMT2AALDH1A1ERN1CTSB | |
| SCHEMBL8398671 | 0.80 | TDP1 (0.49) | MEN1KMT2AALDH1A1CYP19A1CTSB | |
| SCHEMBL28026694 | 0.80 | TDP1 (0.49) | MEN1KMT2AALDH1A1CYP19A1CTSB | |
| SCHEMBL27556368 | 0.80 | ALDH1A1 (0.51) | CDC25CALDH1A1ERN1CTSBGAA | |
| SCHEMBL6688354 | 0.78 | ALDH1A1 (0.53) | MGLLKMT2AALDH1A1TAAR1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1310479-B1 | Process for the preparation of 2-aminomethyl-1,4-diamino-benzene and salts thereof | WELLA AG (DE) | 2004-10-27 | — | — | EP | claimed |
| EP-1310479-A1 | Process for the preparation of 2-aminomethyl-1,4-diamino-benzene and salts thereof | Wella Aktiengesellschaft (DE) | 2003-05-14 | — | — | EP | claimed |
| EP-1110942-A2 | Process for the preparation of 2-aminomethyl-1,4-diamino-benzene and salts thereof, and their use in dyeing composition for keratin fibers | Wella Aktiengesellschaft (DE) | 2001-06-27 | — | — | EP | claimed |
| EP-1310479-B1 | Process for the preparation of 2-aminomethyl-1,4-diamino-benzene and salts thereof | WELLA AG (DE) | 2004-10-27 | — | — | EP | disclosed |
| EP-1310479-A1 | Process for the preparation of 2-aminomethyl-1,4-diamino-benzene and salts thereof | Wella Aktiengesellschaft (DE) | 2003-05-14 | — | — | EP | disclosed |
| EP-1310479-A1 | Process for the preparation of 2-aminomethyl-1,4-diamino-benzene and salts thereof | Wella Aktiengesellschaft (DE) | 2003-05-14 | — | — | EP | disclosed |
| US-6461390-B1 | Process for making 2-aminomethyl-1, 4-diaminobenzene and its salts and compositions and methods for dyeing keratin fibers using same | WELLA AKTIENGESELLSCHAFT (DE) | 2002-10-08 | — | — | US | disclosed |
| US-6461390-B1 | Process for making 2-aminomethyl-1, 4-diaminobenzene and its salts and compositions and methods for dyeing keratin fibers using same | WELLA AKTIENGESELLSCHAFT (DE) | 2002-10-08 | — | — | US | disclosed |
| EP-1110942-A3 | Process for the preparation of 2-aminomethyl-1,4-diamino-benzene and salts thereof, and their use in dyeing composition for keratin fibers | Wella Aktiengesellschaft (DE) | 2002-02-06 | — | — | EP | disclosed |
| EP-1110942-A2 | Process for the preparation of 2-aminomethyl-1,4-diamino-benzene and salts thereof, and their use in dyeing composition for keratin fibers | Wella Aktiengesellschaft (DE) | 2001-06-27 | — | — | EP | disclosed |
| EP-1110942-A2 | Process for the preparation of 2-aminomethyl-1,4-diamino-benzene and salts thereof, and their use in dyeing composition for keratin fibers | Wella Aktiengesellschaft (DE) | 2001-06-27 | — | — | EP | disclosed |
| JP-2001172231-A | METHOD FOR PRODUCING 2-AMINOMETHYL-1,4-DIAMINO-BENZENE AND ITS SALT AND USE OF THESE COMPOUNDS AS DYEING AGENT FOR KERATIN FIBER | WELLA AG | 2001-06-26 | — | — | JP | disclosed |