Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 6/20 | 0.37 |
| ▸ | THRA | P10827 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | PLK1 | P53350 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10433279 | 0.84 | KCNH2 (0.40) | THRBTHRANPC1MAPTRAB9A | |
| SCHEMBL6704209 | 0.81 | THRB (0.44) | THRBTHRAHSD17B10KMT2AESR1 | |
| SCHEMBL10615622 | 0.78 | THRB (0.35) | THRBTHRANPC1MAPTRAB9A | |
| SCHEMBL18905529 | 0.78 | THRB (0.40) | THRBTHRAHSD17B10KMT2AESR1 | |
| SCHEMBL10615003 | 0.77 | THRA (0.55) | THRBTHRAHSD17B10CYP4A11KMT2A | |
| SCHEMBL3481791 | 0.77 | CYP1A2 (0.50) | MAPTKMT2AMEN1 | |
| SCHEMBL13619944 | 0.75 | CA2 (0.50) | THRBTHRAMAPTHSD17B10CYP4A11 | |
| SCHEMBL1363306 | 0.75 | THRB (0.55) | THRBTHRANPC1MAPTRAB9A | |
| SCHEMBL18905547 | 0.74 | THRA (0.45) | THRBTHRAHSD17B10CYP4A11KMT2A | |
| SCHEMBL9806339 | 0.74 | HDAC1 (0.50) | NPC1RAB9AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0823450-B1 | COMPOSITE AND MOLDINGS PRODUCED THEREFROM | MITSUBISHI RAYON CO (JP) | 2004-11-24 | — | — | EP | disclosed |
| US-5939471-A | COLLOIDAL SILICA DISPERSED IN RESIN | MITSUBISHI RAYON CO., LTD. (JP) | 1999-08-17 | — | — | US | disclosed |
| EP-0823450-A1 | COMPOSITE AND MOLDINGS PRODUCED THEREFROM | MITSUBISHI RAYON CO., LTD. (JP) | 1998-02-11 | — | — | EP | disclosed |