Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NAAA | Q02083 | 7/20 | 0.39 |
| ▸ | MMP1 | P03956 | 4/20 | 0.37 |
| ▸ | MMP9 | P14780 | 3/20 | 0.37 |
| ▸ | MMP7 | P09237 | 2/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | P4HB | P07237 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6980239 | 0.80 | CTSD (0.43) | MAPTKMT2AATMMEN1MMP1 | |
| SCHEMBL4242937 | 0.70 | KMT2A (0.36) | MAPTKMT2AATMMEN1NAAA | |
| SCHEMBL7702898 | 0.68 | CA1 (0.46) | KMT2ANOS1NOS2 | |
| SCHEMBL993726 | 0.68 | CA1 (0.42) | KMT2ANOS1NOS2 | |
| SCHEMBL21292118 | 0.67 | MMP1 (0.41) | MAPTKMT2AATMMEN1MMP1 | |
| SCHEMBL15543511 | 0.66 | IDE (0.41) | MAPTKMT2AATMMEN1NAAA | |
| SCHEMBL28982756 | 0.66 | IDE (0.41) | MAPTKMT2AATMMEN1NAAA | |
| SCHEMBL12130902 | 0.66 | — | — | |
| SCHEMBL25421886 | 0.66 | — | — | |
| SCHEMBL9781806 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004089362-A1 | 2-CYANOPYRROLES AND THEIR ANALOGUES AS DDP-IV INHIBITORS | NOVO NORDISK A/S (DK) | 2004-10-21 | — | — | WO | disclosed |